TRIHEPTANOIN
Modify Date: 2024-01-02 18:32:38
TRIHEPTANOIN structure
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Common Name | TRIHEPTANOIN | ||
|---|---|---|---|---|
| CAS Number | 620-67-7 | Molecular Weight | 428.603 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 470.0±12.0 °C at 760 mmHg | |
| Molecular Formula | C24H44O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 195.5±19.6 °C | |
Use of TRIHEPTANOINTriheptanoin (Propane-1,2,3-triyl triheptanoate) is a synthetic medium-chain triglyceride (MCT) consisting of three odd-chain 7-carbon (heptanoate) fatty acids on a glycerol backbone. Triheptanoin can be used for the research of inherited metabolic disorders[1]. |
| Name | triheptanoin |
|---|---|
| Synonym | More Synonyms |
| Description | Triheptanoin (Propane-1,2,3-triyl triheptanoate) is a synthetic medium-chain triglyceride (MCT) consisting of three odd-chain 7-carbon (heptanoate) fatty acids on a glycerol backbone. Triheptanoin can be used for the research of inherited metabolic disorders[1]. |
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| Related Catalog | |
| In Vivo | In long-chain fatty acid oxidation disorders (LC-FAOD), Triheptanoin is used as an anaplerotic compound, acting as a source of calories and fatty acids to bypass the LC-FAOD enzyme deficiencies[1]. Triheptanoin can be used for the research of ataxia-telangiectasia (A-T)[2]. Triheptanoin functions as an anaplerotic agent replenishing tricarboxylic acid (TCA) cycle intermediates by metabolism to heptanoate (C7) and subsequently acetyl-CoA and propionyl-CoA that feed into the TCA cycle to supply energy[2]. Triheptanoin mitigates brain ATP depletion and mitochondrial dysfunction, including respiration and redox balance in a mouse model of Alzheimer's disease, supporting the energy failure hypothesis for that disorder[2]. Triheptanoin (Mice were treated with Triheptanoin (35E%) for 10 days prior to pilocarpine injection to induce status epilepticus) preserved mitochondrial functions in the hippocampal formations of pilocarpine-induced status epilepticus (SE) mice[3]. Animal Model: 7-8 week old male CD1 (35-40 g)[3] Dosage: 35E% oral Triheptanoin was mixed into mouse chow Administration: Given 35E% Triheptanoin treatment 10 days prior to SE induction Result: Preserved mitochondrial functions in SE mice. |
| References |
[1]. Matt Shirley. Triheptanoin: First Approval. Drugs. 2020 Oct;80(15):1595-1600. |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 470.0±12.0 °C at 760 mmHg |
| Molecular Formula | C24H44O6 |
| Molecular Weight | 428.603 |
| Flash Point | 195.5±19.6 °C |
| Exact Mass | 428.313782 |
| PSA | 78.90000 |
| LogP | 7.73 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.457 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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TRIHEPTANOIN CAS#:620-67-7 |
| Literature: Ozaki Biochemische Zeitschrift, 1926 , vol. 177, p. 166 Proceedings of the Imperial Academy (Tokyo), vol. 2, p. 343 Chem. Zentralbl., 1926 , vol. 97, # II p. 2451 |
| Precursor 2 | |
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| DownStream 0 | |
| HS Code | 2915900090 |
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| Summary | 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0% |
| Triheptanoin |
| Glycerol-1,2,3-triheptanoate |
| TRIHEPTANION |
| trioenanthoin |
| Propane-1,2,3-triyl triheptanoate |
| trienanthoin |
| propane-1,2,3-triyl trisheptanoate |
| 1,2,3-Propanetriyl triheptanoate |
| glyceryl triheptanoate |
| glycerol trienanthate |
| 1,2,3-tris-heptanoyloxy-propane |
| glyceroltriheptanoate |
| triheptylin |
| tri-heptanoi |
| 1,2,3-Tris-heptanoyloxy-propan |
| Heptanoic acid, 1,2,3-propanetriyl ester |
| triheptanoicglyceride |
| TRIOENANTHIN |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: TRIHEPTANOIN
- Price: Click To Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: TRIHEPTANOIN
- Price: ￥1890.0/5ml ￥3590.0/25ml
- Purity: 94.0%
- Delivery: Inquiry
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Triheptanoin
- Price: ￥Inquiry/250mg ￥Inquiry/100mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 1 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Triheptanoin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥500/10 mg
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