SARS-CoV-2 3CLpro-IN-13
Modify Date: 2025-08-26 01:03:01
SARS-CoV-2 3CLpro-IN-13 structure
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Common Name | SARS-CoV-2 3CLpro-IN-13 | ||
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| CAS Number | 622794-09-6 | Molecular Weight | 328.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H16N4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SARS-CoV-2 3CLpro-IN-13SARS-CoV-2 3CLpro-IN-13 is a potent SARS-CoV-2 3CL protease inhibitor with an IC50 value of 21 nM. SARS-CoV-2 3CLpro-IN-13 shows anti-coronavirus activity[1]. |
| Name | SARS-CoV-2 3CLpro-IN-13 |
|---|
| Description | SARS-CoV-2 3CLpro-IN-13 is a potent SARS-CoV-2 3CL protease inhibitor with an IC50 value of 21 nM. SARS-CoV-2 3CLpro-IN-13 shows anti-coronavirus activity[1]. |
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| Related Catalog | |
| Target |
IC50: 21 nM (SARS-CoV-2 3CL protease)[1] |
| In Vitro | SARS-CoV-2 3CLpro-IN-13 (compound 1) 显示出抗冠状病毒活性，对于 hCoV-229E (Alpha-CoV) 3CLpro，SARS-CoV-2 (Beta-CoV) 3CLpro、SARS-CoV (Beta-CoV) 3CLpro、MERS-CoV (Beta-CoV) 3CLpro 的 IC50 值分别为 0.016、0.021、0.383、2.00 µM，[1]。 SARS-CoV-2 3CLpro-IN-13 (0-300 µM) 对人半胱氨酸蛋白酶具有选择性，对3CLpro SARS-CoV-2，human calpain 1, Cathepsin L 的 IC50 值分别为 1.46、>300、122 µM[1]。 SARS-CoV-2 3CLpro-IN-13 (0.1-10 µM) 具有抗病毒活性，对 SARS-CoV-2 和人类冠状病毒 229E 的 IC50 值分别为 1.06、1.34 µM [1]。 |
| References |
| Molecular Formula | C16H16N4S2 |
|---|---|
| Molecular Weight | 328.46 |