Octanoic acid,1,1'-(1,2-ethanediyl) ester

Modify Date: 2024-01-11 11:12:02

Octanoic acid,1,1'-(1,2-ethanediyl) ester Structure
Octanoic acid,1,1'-(1,2-ethanediyl) ester structure
Common Name Octanoic acid,1,1'-(1,2-ethanediyl) ester
CAS Number 627-86-1 Molecular Weight 314.46000
Density 0.945g/cm3 Boiling Point 387.1ºC at 760 mmHg
Molecular Formula C18H34O4 Melting Point N/A
MSDS Chinese USA Flash Point 179.8ºC

 Use of Octanoic acid,1,1'-(1,2-ethanediyl) ester


Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor (Ki of 58 μM)[1].

 Names

Name 1,2-Dioctanoylethylene glycol
Synonym More Synonyms

  Biological Activity

Description Dioctanoylglycol (Ethylene glycol dicaprylate), a diacylglycerol analog, is a diacylglycerol kinase (DGK) inhibitor (Ki of 58 μM)[1].
Related Catalog
In Vitro Dioctanoylglycol (Dioctanoylethylene glycol) inhibits diacylglycerol phosphorylation in platelets (70-100% at 100 μM) leading to a longer-lived diacylglycerol signal[1].
References

[1]. W R Bishop, et al. Attenuation of sn-1,2-diacylglycerol second messengers by diacylglycerol kinase. Inhibition by diacylglycerol analogs in vitro and in human platelets. J Biol Chem. 1986 May 25;261(15):6993-7000.

 Chemical & Physical Properties

Density 0.945g/cm3
Boiling Point 387.1ºC at 760 mmHg
Molecular Formula C18H34O4
Molecular Weight 314.46000
Flash Point 179.8ºC
Exact Mass 314.24600
PSA 52.60000
LogP 4.79380
Index of Refraction 1.447
Storage condition -20°C

 Safety Information

RIDADR NONH for all modes of transport
HS Code 2915900090

 Synthetic Route

~88%

Octanoic acid,1,1'-(1,2-ethanediyl) ester Structure

Octanoic acid,1...

CAS#:627-86-1

Literature: Vista Chemical Company Patent: US5386045 A1, 1995 ;

~82%

Octanoic acid,1,1'-(1,2-ethanediyl) ester Structure

Octanoic acid,1...

CAS#:627-86-1

Literature: Lin, Gialih; Lu, Chin-Ping Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 301 - 306

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Octanoic acid,1,1'-(1,2-ethanediyl) ester Structure

Octanoic acid,1...

CAS#:627-86-1

Literature: JAOCS, Journal of the American Oil Chemists' Society, , vol. 83, # 3 p. 201 - 207

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Octanoic acid,1,1'-(1,2-ethanediyl) ester Structure

Octanoic acid,1...

CAS#:627-86-1

Literature: Fette und Seifen, , vol. 57, p. 652,656 Grasas Aceites, , vol. 7, p. 286,292

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Articles6

More Articles
Attenuation of sn-1,2-diacylglycerol second messengers by diacylglycerol kinase. Inhibition by diacylglycerol analogs in vitro and in human platelets.

J. Biol. Chem. 261 , 6993, (1986)

Diacylglycerol kinase is though to play a central role in the metabolism of diacylglycerol second messengers in agonist-stimulated cells. A series of diacylglycerol analogs were tested for their abili...

Peroxides of vanadate induce activation of phospholipase D in HL-60 cells. Role of tyrosine phosphorylation.

J. Biol. Chem. 267(17) , 11908-16, (1992)

To determine the role of protein tyrosine phosphorylation in the activation of phospholipase D (PLD), electropermeabilized HL-60 cells labeled in [3H]alkyl-phosphatidylcholine were treated with vanada...

Phosphocholine transferase is more efficient than diacylglycerol kinase as possible attenuator of diacylglycerol signals in primordial human placenta.

Acta Physiol. Hung. 81(4) , 341-54, (1993)

Diacylglycerols (DAG) are assumed to play intracellular signal roles in rapidly growing tissues like those present in the primordial human placenta. The aim of the present study was to gain informatio...

 Synonyms

2-octanoyloxyethyl octanoate
MFCD00058489