Mulberrin

Modify Date: 2024-01-08 19:24:32

Mulberrin Structure
Mulberrin structure
 Common Name Mulberrin
CAS Number 62949-79-5 Molecular Weight 422.470
Density 1.3±0.1 g/cm3 Boiling Point 657.7±55.0 °C at 760 mmHg
Molecular Formula C25H26O6 Melting Point 153-156 °C
MSDS N/A Flash Point 225.0±25.0 °C

 Use of Mulberrin


Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM.

 Names

Name 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methylbut-2-enyl)chromen-4-one
Synonym More Synonyms

 Mulberrin Biological Activity

Description Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM.
Related Catalog
In Vitro Mulberrin is a flavone with two isopentenyl groups at positions 3 and 8. Mulberrin is a strong inhibitor of OATP2B1 with more than 80% inhibition.Mulberrin also inhibits organic anion-transporting polypeptide (OATP)-mediated uptake of Atorvastatin, Fluvastatin, and Rosuvastatin[1].
References

[1]. Wen F, et al. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake. Pharm Biol. 2016;54(2):293-302.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 657.7±55.0 °C at 760 mmHg
Melting Point 153-156 °C
Molecular Formula C25H26O6
Molecular Weight 422.470
Flash Point 225.0±25.0 °C
Exact Mass 422.172943
PSA 111.13000
LogP 5.78
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.642
Storage condition 2-8°C

 Synonyms

Norartocarpin
2-(2,4-Dihydroxy-phenyl)-5,7-dihydroxy-8-((Z)-3-methyl-but-2-enyl)-3-(3-methyl-but-2-enyl)-1-benzopyran-4-one
2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-buten-1-yl)-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-buten-1-yl)-
Kuwanon C
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Chemsrc provides Mulberrin(CAS#:62949-79-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Mulberrin are included as well.>> amp version: Mulberrin

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