2,4-Imidazolidinedione,5-ethyl-5-phenyl-

Modify Date: 2025-08-23 12:40:03

2,4-Imidazolidinedione,5-ethyl-5-phenyl- structure	Common Name	2,4-Imidazolidinedione,5-ethyl-5-phenyl-
	CAS Number	631-07-2	Molecular Weight	204.22500
	Density	1.173 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₂N₂O₂	Melting Point	195-200ºC
	MSDS	USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Name	rac N-Desmethyl Mephenytoin
Synonym	More Synonyms

Density	1.173 g/cm3
Melting Point	195-200ºC
Molecular Formula	C₁₁H₁₂N₂O₂
Molecular Weight	204.22500
Exact Mass	204.09000
PSA	58.20000
LogP	1.78890
Index of Refraction	1.538
Storage condition	2-8°C

2,4-Imidazolidinedione,5-ethyl-5-phenyl- MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MU2452000

CHEMICAL NAME :: Hydantoin, 5-ethyl-5-phenyl-

CAS REGISTRY NUMBER :: 631-07-2

LAST UPDATED :: 199012

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C11-H12-N2-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: LDTU** "Narkoseversuche mit Hoheren Alkoholen und Stickstoffderivaten, Dissertation," Leube, F., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1931 Volume(issue)/page/year: -,-,1931

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement

REFERENCE :: HDTU** "Pharmakologische Prufung von Analgetika, Dissertation," Herrlen, G., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1933 Volume(issue)/page/year: -,-,1933

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	26
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	MU2452000

2-isocyanato-2-...

CAS#:33875-36-4

2,4-Imidazolidi...

CAS#:631-07-2

Literature: Archiv der Pharmazie (Weinheim, Germany), , vol. 313, # 6 p. 538 - 543

(1-cyano-1-phen...

CAS#:75356-44-4

2,4-Imidazolidi...

CAS#:631-07-2

Literature: Archiv der Pharmazie (Weinheim, Germany), , vol. 313, # 6 p. 538 - 543

Precursor 1
CAS#:33875-36-4 2-isocyanato-2-...
DownStream 0

Pharmacodynamics of cytochrome P450 2B induction by phenobarbital, 5-ethyl-5-phenylhydantoin, and 5-ethyl-5-phenyloxazolidinedione in the male rat liver or in cultured rat hepatocytes.

Chem. Res. Toxicol. 6(2) , 188-96, (1993)

The pharmacodynamics of rat hepatic cytochrome P450 2B (P450 2B) induction by phenobarbital (PB) and two structural congeners, dl-5-ethyl-5-phenylhydantoin (EPH) and dl-5-ethyl-5-phenyloxazolidinedion...

A markedly diminished pleiotropic response to phenobarbital and structurally-related xenobiotics in Zucker rats in comparison with F344/NCr or DA rats.

Biochem. Pharmacol. 43(5) , 1079-87, (1992)

Phenobarbital (PB) and certain structurally-related compounds induce a variety of hepatic drug-metabolizing enzymes in many strains of rats. Thus, following administration of PB (300, 500 ppm), barbit...

Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors.

Arch. Biochem. Biophys. 429(1) , 1-15, (2004)

Three series of N-3 alkyl substituted phenytoin, nirvanol, and barbiturate derivatives were synthesized and their inhibitor potencies were tested against recombinant CYP2C19 and CYP2C9 to probe the in...

EINECS 211-150-3

(+/-)-5-ethyl-5-phenylhydantoin

MFCD00022401

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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,4-Imidazolidinedione,5-ethyl-5-phenyl-
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Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: rac N-Desmethyl Mephenytoin
Price: ￥Inquiry/100mg ￥Inquiry/1g ￥Inquiry/250mg
Purity: 95.0%
Delivery: Inquiry
Contact: Xiyao Wang
Email: 3623107365@qq.com

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2,4-Imidazolidinedione,5-ethyl-5-phenyl-

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Articles25

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.