VUF 5681 dihydrobromide

Modify Date: 2025-08-26 11:28:32

VUF 5681 dihydrobromide Structure
VUF 5681 dihydrobromide structure
 Common Name VUF 5681 dihydrobromide
CAS Number 639089-06-8 Molecular Weight 355.11
Density N/A Boiling Point N/A
Molecular Formula C11H21Br2N3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VUF 5681 dihydrobromide


VUF 5681 dihydrobromide is a neutral antagonist of histamine H3 receptor. VUF 5681 dihydrobromide also has partial agonist function of H3 receptor. VUF 5681 dihydrobromide blocks the effects of Thioperamide (HY-12206). VUF 5681 dihydrobromide is used in central nervous system disease research[1][2].

 Names

Name 4-[3-(1H-imidazol-5-yl)propyl]piperidine,dihydrobromide
Synonym More Synonyms

 VUF 5681 dihydrobromide Biological Activity

Description VUF 5681 dihydrobromide is a neutral antagonist of histamine H3 receptor. VUF 5681 dihydrobromide also has partial agonist function of H3 receptor. VUF 5681 dihydrobromide blocks the effects of Thioperamide (HY-12206). VUF 5681 dihydrobromide is used in central nervous system disease research[1][2].
Related Catalog
Target

H3 receptor

References

[1]. Moreno-Delgado D, et al. Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway. Neuropharmacology. 2006 Sep;51(3):517-23.  

[2]. Baker JG. Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells. BMC Pharmacol. 2008 Jun 6;8:9.  

 Chemical & Physical Properties

Molecular Formula C11H21Br2N3
Molecular Weight 355.11
Exact Mass 353.01000
PSA 40.71000
LogP 3.97700

 Synonyms

Pentoxyresorufin
VUF 5681 dihydrobromide
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