PPIase-Parvulin Inhibitor
PPIase-Parvulin Inhibitor structure
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Common Name | PPIase-Parvulin Inhibitor | ||
|---|---|---|---|---|
| CAS Number | 64005-90-9 | Molecular Weight | 438.38700 | |
| Density | 1.471g/cm3 | Boiling Point | 636.5ºC at 760 mmHg | |
| Molecular Formula | C22H18N2O8 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 338.7ºC | |
| Symbol |
GHS09 |
Signal Word | Warning | |
Use of PPIase-Parvulin InhibitorPPIase-Parvulin Inhibitor is a cell-permeable inhibitor of the PPIases Pin1 and Pin4 with IC50s of 1.5 and 1.0 µM, respectively[1]. |
| Name | PPIase-Parvulin Inhibitor |
|---|---|
| Synonym | More Synonyms |
| Description | PPIase-Parvulin Inhibitor is a cell-permeable inhibitor of the PPIases Pin1 and Pin4 with IC50s of 1.5 and 1.0 µM, respectively[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.471g/cm3 |
|---|---|
| Boiling Point | 636.5ºC at 760 mmHg |
| Molecular Formula | C22H18N2O8 |
| Molecular Weight | 438.38700 |
| Flash Point | 338.7ºC |
| Exact Mass | 438.10600 |
| PSA | 130.74000 |
| LogP | 0.19180 |
| Index of Refraction | 1.641 |
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~%
PPIase-Parvulin... CAS#:64005-90-9 |
| Literature: Fierz-David; Rossi Helvetica Chimica Acta, 1938 , vol. 21, p. 1466,1479, 1480 |
| Precursor 2 | |
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| DownStream 0 | |
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FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice.
EJNMMI Res. 5 , 20, (2015) Over the last decade, an increasing number of studies have been published on the use of amyloid-β (Aβ) PET imaging with different (18)F-radiopharmaceuticals for clinical characterization of Alzheimer'... |
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Amyloid Beta-Weighted Cortical Thickness: A New Imaging Biomarker in Alzheimer's Disease.
Curr. Alzheimer Res. 12 , 563-71, (2015) Alzheimer's disease (AD) is the most common neurodegenerative disorder pathologically characterized by amyloid-beta (Aβ) plaques and neurofibrillary tangles. The aggregation of Aβ precedes tau patholo... |
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Depressive Symptoms and Biomarkers of Alzheimer's Disease in Cognitively Normal Older Adults.
J. Alzheimers Dis. 46 , 63-73, (2015) Even low levels of depressive symptoms are associated with an increased risk of cognitive decline in older adults without overt cognitive impairment (CN). Our objective was to examine whether very low... |
| IN1141 |
| diethyl 1,3,6,8-tetrahydro-1,3,6,8-tetraoxobenzo[lmn][3,8]phenanthroline-2,7-diacetate |
| phenanthroline-(2H,7H)-diacetate |
| (1,3,6,8-Tetraoxo-1,3,6,8-tetrahydro-benzo[lmn][3,8]phenanthrolin-2,7-diyl)-di-essigsaeure-diaethylester |
| (1,3,6,8-tetraoxo-1,3,6,8-tetrahydro-benzo[lmn][3,8]phenanthroline-2,7-diyl)-di-acetic acid diethyl ester |
| phenanthroline-2,7-diacetate |
| HIC 016C |
| (1,3,6,8-tetraoxo-1,3,6,8-tetrahydro-benzo[lmn][3,8]phenanthroline-2,7-diyl)-bis-acetic acid diethyl ester |