kanamycin acid sulfate structure
|
Common Name | kanamycin acid sulfate | ||
|---|---|---|---|---|
| CAS Number | 64013-70-3 | Molecular Weight | 680.65600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H40N4O19S2 | Melting Point | >260℃ | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS08 |
Signal Word | Danger | |
| Name | (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol,sulfuric acid |
|---|---|
| Synonym | More Synonyms |
| Melting Point | >260℃ |
|---|---|
| Molecular Formula | C18H40N4O19S2 |
| Molecular Weight | 680.65600 |
| Exact Mass | 680.17300 |
| PSA | 448.57000 |
| Appearance of Characters | white to off-white |
| Storage condition | 2-8°C |
| Water Solubility | Soluble in aqueous solutions |
| Symbol |
GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H360 |
| Precautionary Statements | P201-P308 + P313 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Phrases | 61 |
| Safety Phrases | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29419000 |
| HS Code | 29419000 |
|---|
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Loss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephone.
PLoS Genet. 8(10) , e1002971, (2012) Mechanosensory hair cell death is a leading cause of hearing and balance disorders in the human population. Hair cells are remarkably sensitive to environmental insults such as excessive noise and exp... |
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Aminoglycosides inhibit KCNQ4 channels in cochlear outer hair cells via depletion of phosphatidylinositol(4,5)bisphosphate.
Mol. Pharmacol. 79 , 51-60, (2011) Aminoglycoside antibiotics (AGs) are severely ototoxic. AGs cause degeneration of outer hair cells (OHCs), leading to profound and irreversible hearing loss. The underlying mechanisms are not fully un... |
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Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes.
Nat. Commun. 6 , 7385, (2015) Predicting evolutionary paths to antibiotic resistance is key for understanding and controlling drug resistance. When considering a single final resistant genotype, epistatic contingencies among mutat... |
| Kanamycin A sulfate |
| Kanamycin disulfate salt from Streptomyces kanamyceticus |
| kanamycin A sulphate |
| Canamycin A disulfate |
| canamycin monosulfate |
| kanA sulfate |
| EINECS 246-933-9 |
| kanamycin A monosulfate |