Allomatrine

Modify Date: 2025-08-23 16:08:01

Allomatrine structure	Common Name	Allomatrine
	CAS Number	641-39-4	Molecular Weight	347.364
	Density	1.4±0.1 g/cm3	Boiling Point	638.7±55.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₄N₂O	Melting Point	106-107 â„ƒ
	MSDS	N/A	Flash Point	340.1±31.5 °C

Use of Allomatrine

Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors[1][2].

Name	4-(2-Biphenylyl)-1-(hydroxymethyl)-10-oxa-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
Synonym	More Synonyms

Description	Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Long Pan, et al. Chemical Constituents of Alkaloids From the Bark of Sophora Japonica. Zhong Yao Cai. 2016 Sep;39(9):2027-9. [2]. Seiichi Kobashi , et al. Antinociceptive Effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in Mice: Structure-Activity Relation Study of Matrine-Type Alkaloids. Biol Pharm Bull. 2002 Aug;25(8):1030-4.

Description

Allomatrine ((+)-Allomatrine) is an alkaloid from the bark of Sophora japonica. Allomatrine has antinociceptive properties mediated mainly through the activation ofκ-opioid receptors[1][2].

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

References

[1]. Long Pan, et al. Chemical Constituents of Alkaloids From the Bark of Sophora Japonica. Zhong Yao Cai. 2016 Sep;39(9):2027-9.

[2]. Seiichi Kobashi , et al. Antinociceptive Effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in Mice: Structure-Activity Relation Study of Matrine-Type Alkaloids. Biol Pharm Bull. 2002 Aug;25(8):1030-4.

Density	1.4±0.1 g/cm3
Boiling Point	638.7±55.0 °C at 760 mmHg
Melting Point	106-107 â„ƒ
Molecular Formula	C₁₅H₂₄N₂O
Molecular Weight	347.364
Flash Point	340.1±31.5 °C
Exact Mass	347.115753
PSA	66.84000
LogP	2.09
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.666
InChIKey	ZSBXGIUJOOQZMP-KYEXWDHISA-N
SMILES	O=C1CCCC2C3CCCN4CCCC(CN12)C34
Storage condition	2-8C

Precursor 4
CAS#:519-02-8 Matrine CAS#:1119-46-6 5-Chloropentano... CAS#:1575-61-7 5-Chlorovaleryl... CAS#:1121-89-7 Glutarimide
DownStream 0

Name: Antiviral activity against HBV infected in human HepG2.2.15 cells assessed as inhibit...
Source: ChEMBL
Target: Hepatitis B virus
External Id: CHEMBL4202361

Name: Inhibition of HBeAg release against HBV in HepG2 2.2.15 cell line at 0.1 umol/mL
Source: ChEMBL
Target: Hepatitis B virus
External Id: CHEMBL866534

Name: Inhibition of HBeAg release against HBV in HepG2 2.2.15 cell line at 0.2 umol/mL
Source: ChEMBL
Target: Hepatitis B virus
External Id: CHEMBL866533

Name: Inhibition of HBsAg release against HBV in HepG2 2.2.15 cell line at 0.1 umol/mL
Source: ChEMBL
Target: Hepatitis B virus
External Id: CHEMBL866532

Name: Inhibition of HBsAg release against HBV in HepG2 2.2.15 cell line at 0.2 umol/mL
Source: ChEMBL
Target: Hepatitis B virus
External Id: CHEMBL866531

Name: Cytotoxicity against human HepG2.2.15 cells assessed as growth inhibition at 0.8 mM b...
Source: ChEMBL
Target: HepG2 2.2.15
External Id: CHEMBL4202369

Name: Cytotoxicity against HepG2 2.2.15 cell line at 0.4 umol/mL by MTT assay
Source: ChEMBL
Target: HepG2
External Id: CHEMBL866535

Name: Antiviral activity against HBV infected in human HepG2.2.15 cells assessed as inhibit...
Source: ChEMBL
Target: Hepatitis B virus
External Id: CHEMBL4202365

Total 8, Current Page 1 of 1

13S-HYDROXY-6Z,9Z,11E-OCTADECATRIENOIC ACID

4-(2-Biphenylyl)-1-(hydroxymethyl)-10-oxa-4-azatricyclo[5.2.1.0]dec-8-ene-3,5-dione

13-hydroxy-(6Z,9Z,11E,13S)-6,9,11-octadecatrienoic acid

13(S)-HYDROXY-9(Z),11(E),15(Z)-OCTADECATRIENOIC ACID

(13S,6Z,9Z,11E)-hydroxyoctadeca-6,9,11-trienoic acid

Allomatrine

13-hydroxy-6,9,11-octadecatrienoic acid

(+)-Allomatrin

13(S)-HOT

13(S)-HYDROXYOCTADECA-6Z,9Z,11E-TRIENOIC ACID

13(S)-HOTE

(6Z,9Z,11E)-13(S)-hydroxyoctadeca-6,9,11-trienoic acid

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Allomatrine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ALLOMATRINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Allomatrine
Price: ￥148.0/20mg
Purity: 98.0%
Delivery: 1 Day
Contact: Liu jia
Email: 2130147988@qq.com

Get all suppliers and price by the below link:

Allomatrine suppliers

Allomatrine price

Allomatrine

Use of Allomatrine

Names

Allomatrine Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

AllomatrineBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.