N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate

Modify Date: 2024-01-02 20:31:24

N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate structure	Common Name	N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
	CAS Number	64987-85-5	Molecular Weight	334.324
	Density	1.4±0.1 g/cm3	Boiling Point	501.7±42.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₈N₂O₆	Melting Point	180-182 °C(lit.)
	MSDS	Chinese USA	Flash Point	257.2±27.9 °C

Use of N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate

SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses[1].

Name	succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Synonym	More Synonyms

Description	SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Guo Y, et al. Potent antigen-specific immune response induced by infusion of spleen cells coupled with succinimidyl-4-(N-maleimidomethyl cyclohexane)-1-carboxylate (SMCC) conjugated antigens. Int Immunopharmacol. 2016 Feb;31:158-68.

Density	1.4±0.1 g/cm3
Boiling Point	501.7±42.0 °C at 760 mmHg
Melting Point	180-182 °C(lit.)
Molecular Formula	C₁₆H₁₈N₂O₆
Molecular Weight	334.324
Flash Point	257.2±27.9 °C
Exact Mass	334.116486
PSA	101.06000
LogP	-0.39
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.598
Storage condition	2-8°C
Water Solubility	chloroform: 50 mg/mL

MSDS(Chinese)

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2925190090

N-Hydroxysuccinimide

CAS#:6066-82-6

N-Succinimidyl ...

CAS#:64987-85-5

Literature: Journal of Pharmaceutical Sciences, , vol. 75, # 7 p. 711 - 713

Precursor 1
CAS#:6066-82-6 N-Hydroxysuccinimide
DownStream 0

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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MFCD00009634

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N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate

1-[(4-{[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione

1H-pyrrole-2,5-dione, 1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-

N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate