5-CHLORO-2-(TRIFLUOROMETHYL)BENZIMIDAZOLE

Modify Date: 2026-07-15 19:40:51

5-CHLORO-2-(TRIFLUOROMETHYL)BENZIMIDAZOLE structure	Common Name	5-CHLORO-2-(TRIFLUOROMETHYL)BENZIMIDAZOLE
	CAS Number	656-49-5	Molecular Weight	220.57900
	Density	1.569 g/cm3	Boiling Point	301ºC at 760 mmHg
	Molecular Formula	C₈H₄ClF₃N₂	Melting Point	N/A
	MSDS	N/A	Flash Point	135.9ºC

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	6-chloro-2-(trifluoromethyl)-1H-benzimidazole
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.569 g/cm3
Boiling Point	301ºC at 760 mmHg
Molecular Formula	C₈H₄ClF₃N₂
Molecular Weight	220.57900
Flash Point	135.9ºC
Exact Mass	220.00200
PSA	28.68000
LogP	3.23510
Index of Refraction	1.575
InChIKey	OQKQEDXERMELRT-UHFFFAOYSA-N
SMILES	FC(F)(F)c1nc2ccc(Cl)cc2[nH]1

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DD7000000

CHEMICAL NAME :: Benzimidazole, 5-chloro-2-(trifluoromethyl)-

CAS REGISTRY NUMBER :: 656-49-5

LAST UPDATED :: 199007

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H4-Cl-F3-N2

MOLECULAR WEIGHT :: 220.59

WISWESSER LINE NOTATION :: T56 BM DNJ CXFFF GG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6817 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSSCBG Pesticide Science. (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1- 1970- Volume(issue)/page/year: 15,31,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 46 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 18,1389,1969

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code	2933990090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

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Literature: Navarrete-Vazquez, Gabriel; Rojano-Vilchis, Maria De Monserrat; Yepez-Mulia, Lilian; Melendez, Victor; Gerena, Lucia; Hernandez-Campos, Alicia; Castillo, Rafael; Hernandez-Luis, Francisco European Journal of Medicinal Chemistry, 2006 , vol. 41, # 1 p. 135 - 141

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: In vitro antiprotozoal activity against Giardia lamblia
Source: ChEMBL
Target: Giardia intestinalis
External Id: CHEMBL857381

Name: In vitro antiprotozoal activity against Entamoeba histolytica
Source: ChEMBL
Target: Entamoeba histolytica
External Id: CHEMBL676675

Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979

Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750

Name: Antiamnesic activity against Entamoeba histolytica
Source: ChEMBL
Target: Entamoeba histolytica
External Id: CHEMBL915565

Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA

Name: Tested for inhibition of tubulin polymerization in rat brain at a concentration of 0....
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL796404

Name: Inhibitors of CDC25B-CDK2/CyclinA interaction
Source: Center for Chemical Genomics, University of Michigan
External Id: MScreen:TargetID_600

Name: High-throughput screen for inhibitors of the GIV GBA-motif interaction with Galpha-i ...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS1303

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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

5-chloro-2-trifluoromethylbenzimidazole

5-chloro-2-trifluoromethyl-1(3)H-benzoimidazole

5-Chlor-2-trifluormethyl-benzimidazol

BENZIMIDAZOLE,5-CHLORO-2-(TRIFLUOROMETHYL)

2-Trifluormethyl-5-chlorbenzimidazol

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the LogP of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole?

A: LogP of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole is 3.23510.

Q: What is the molecular weight of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole?

A: Molecular weight of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole is 220.57900.

Q: What is the SMILES notation of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole?

A: SMILES notation of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole is FC(F)(F)c1nc2ccc(Cl)cc2[nH]1.

Q: What is the InChIKey of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole?

A: InChIKey of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole is OQKQEDXERMELRT-UHFFFAOYSA-N.

Q: What is the boiling point of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole?

A: Boiling point of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole is 301ºC at 760 mmHg.

Q: What English synonyms does 6-chloro-2-(trifluoromethyl)-1H-benzimidazole have?

A: English synonyms of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole: 5-chloro-2-trifluoromethylbenzimidazole, 5-chloro-2-trifluoromethyl-1(3)H-benzoimidazole, 5-Chlor-2-trifluormethyl-benzimidazol, BENZIMIDAZOLE,5-CHLORO-2-(TRIFLUOROMETHYL), 2-Trifluormethyl-5-chlorbenzimidazol.

Q: What is the polar surface area (PSA) of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole?

A: Polar surface area (PSA) of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole is 28.68000.

Q: What is the English name of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole?

A: The English name of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole is 6-chloro-2-(trifluoromethyl)-1H-benzimidazole.

Q: What is the molecular formula of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole?

A: Molecular formula of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole is C8H4ClF3N2.

Q: What is the CAS number of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole?

A: CAS number of 6-chloro-2-(trifluoromethyl)-1H-benzimidazole is 656-49-5.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5-CHLORO-2-(TRIFLUOROMETHYL)BENZIMIDAZOLE
Price: Check
Purity: 97.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-CHLORO-2-(TRIFLUOROMETHYL)BENZIMIDAZOLE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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