(R)-SLV 319

Modify Date: 2025-08-27 09:48:16

(R)-SLV 319 Structure
(R)-SLV 319 structure
Common Name (R)-SLV 319
CAS Number 656827-86-0 Molecular Weight 487.40
Density 1.4±0.1 g/cm3 Boiling Point 623.2±65.0 °C at 760 mmHg
Molecular Formula C23H20Cl2N4O2S Melting Point N/A
MSDS N/A Flash Point 330.7±34.3 °C

 Use of (R)-SLV 319


(R)-SLV 319 is a potent and selective cannabinoid receptor 1 (CB1) antagonist with a Ki value of 894 nM. (R)-SLV 319 is a dextrorotatory counterpart of SLV 319[1]

 Names

Name (4R)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
Synonym More Synonyms

 (R)-SLV 319 Biological Activity

Description (R)-SLV 319 is a potent and selective cannabinoid receptor 1 (CB1) antagonist with a Ki value of 894 nM. (R)-SLV 319 is a dextrorotatory counterpart of SLV 319[1]
Related Catalog
Target

CB1:894 nM (Ki)

References

[1]. Lange JH, et al. Synthesis, biological properties, and molecular modeling investigations of novel 3,4-diarylpyrazolines as potent and selective CB(1) cannabinoid receptor antagonists. J Med Chem. 2004;47(3):627-643.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 623.2±65.0 °C at 760 mmHg
Molecular Formula C23H20Cl2N4O2S
Molecular Weight 487.40
Flash Point 330.7±34.3 °C
Exact Mass 486.068390
PSA 82.51000
LogP 4.67
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.663
InChIKey AXJQVVLKUYCICH-NRFANRHFSA-N
SMILES CN=C(NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1

 Synonyms

1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N'-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N-methyl-4-phenyl-
3-(4-chlorophenyl)-N-methyl-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamidine
3-(4-Chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-N'-methyl-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamide
1H-pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-
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