Hydrastinine

Modify Date: 2025-08-25 17:33:00

Hydrastinine Structure
Hydrastinine structure
Common Name Hydrastinine
CAS Number 6592-85-4 Molecular Weight 207.22600
Density 1.332g/cm3 Boiling Point 342.5ºC at 760 mmHg
Molecular Formula C11H13NO3 Melting Point N/A
MSDS N/A Flash Point 161ºC

 Use of Hydrastinine


Hydrastinine is a major alkaloid constituent in goldenseal (Hydrastis canadensis). Hydrastinine can be used as a haemostatic agent[1].

 Names

Name 6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-ol
Synonym More Synonyms

 Hydrastinine Biological Activity

Description Hydrastinine is a major alkaloid constituent in goldenseal (Hydrastis canadensis). Hydrastinine can be used as a haemostatic agent[1].
Related Catalog
References

[1]. Chen S, et al. Mechanism study of goldenseal-associated DNA damage. Toxicol Lett. 2013 Jul 31;221(1):64-72.

[2]. Freudenmann RW, et al. The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents. Addiction. 2006 Sep;101(9):1241-5.

 Chemical & Physical Properties

Density 1.332g/cm3
Boiling Point 342.5ºC at 760 mmHg
Molecular Formula C11H13NO3
Molecular Weight 207.22600
Flash Point 161ºC
Exact Mass 207.09000
PSA 41.93000
LogP 0.83200
Index of Refraction 1.617
InChIKey YOJQZPVUNUQTDF-UHFFFAOYSA-N
SMILES CN1CCc2cc3c(cc2C1O)OCO3

 Safety Information

RIDADR UN 1544
Packaging Group III
Hazard Class 6.1(b)
HS Code 2934999090

 Synthetic Route

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 HydrastinineBioassay

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Name: Enzymatic assay of human HDAC6 with commercial peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808149
Name: uHTS identification of small molecule modulators of Rev-erb Alpha.
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: SBCCG-A1016-RevErbaLBD-Primary-Assay
Name: Enzymatic assay of human HDAC6 with custom peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808150
Name: Screen for inhibitors of RMI FANCM (MM2) intereaction
Source: 11908
Target: N/A
External Id: RMI-FANCM-MM2
Name: Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H...
Source: Southern Research Institute
Target: CFTR
External Id: CF Folding
Name: The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre...
Source: 11924
Target: N/A
External Id: CGM data for Cell Systems paper Dec 2015
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 Synonyms

hydrastinine
Hydraztinine
6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-ol
EINECS 229-533-9
5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-ol
1,3-Dioxolo(4,5-g)isoquinolin-5-ol,5,6,7,8-tetrahyro-6-methyl
1,3-Dioxolo[4,5-g]isoquinolin-5-ol,5,6,7,8-tetrahydro-6-methyl
1-hydroxy-6,7-methylenedioxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
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