Hydrastine

Modify Date: 2024-01-02 18:44:40

Hydrastine structure	Common Name	Hydrastine
	CAS Number	118-08-1	Molecular Weight	383.39500
	Density	1.339g/cm3	Boiling Point	548.8ºC at 760mmHg
	Molecular Formula	C₂₁H₂₁NO₆	Melting Point	132ºC
	MSDS	N/A	Flash Point	285.7ºC
	Symbol	GHS07	Signal Word	Warning

Use of Hydrastine

Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family.

Name	(-)-β-HYDRASTINE
Synonym	More Synonyms

Description	Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family.
Related Catalog	Signaling Pathways >> Others >> Others Natural Products >> Alkaloid Research Areas >> Others

Density	1.339g/cm3
Boiling Point	548.8ºC at 760mmHg
Melting Point	132ºC
Molecular Formula	C₂₁H₂₁NO₆
Molecular Weight	383.39500
Flash Point	285.7ºC
Exact Mass	383.13700
PSA	66.46000
LogP	2.81110
Vapour Pressure	4.28E-12mmHg at 25°C
Index of Refraction	1.614
Storage condition	−20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MU6030000

CHEMICAL NAME :: Hydrastine

CAS REGISTRY NUMBER :: 118-08-1

BEILSTEIN REFERENCE NO. :: 0098575

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H21-N-O6

MOLECULAR WEIGHT :: 383.43

WISWESSER LINE NOTATION :: T C566 DO FO LN EH&&TJ L M- DT56 BVO DHJ HO1 IO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 104 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302 + H312 + H332
Precautionary Statements	P261-P280-P301 + P312 + P330
Hazard Codes	Xn: Harmful;
Risk Phrases	20/21/22
Safety Phrases	S36
RIDADR	1544
WGK Germany	3
RTECS	MU6030000
Packaging Group	III
Hazard Class	6.1(b)

narcotoline-8-(...

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Hydrastine

CAS#:118-08-1

Literature: Kerekes; Gaal Gy.; Bognar Acta Chimica Academiae Scientiarum Hungaricae, 1980 , vol. 103, # 4 p. 339 - 341

(S)-3-((R)-6,7-...

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Bromochloromethane

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Hydrastine

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Literature: Zelle; McClellan Tetrahedron Letters, 1991 , vol. 32, # 22 p. 2461 - 2464

[S-(R*,R*)]-6,7...

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Hydrastine

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diazomethane

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Hydrastine

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Hydrastine

CAS#:118-08-1

Literature: Journal of the Chemical Society, , p. 1776,1779

Precursor 7
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DownStream 7
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