1,10-Phenanthroline

Modify Date: 2025-08-20 18:12:32

1,10-Phenanthroline structure	Common Name	1,10-Phenanthroline
	CAS Number	66-71-7	Molecular Weight	180.205
	Density	1.3±0.1 g/cm3	Boiling Point	365.1±15.0 °C at 760 mmHg
	Molecular Formula	C₁₂H₈N₂	Melting Point	114-117 °C(lit.)
	MSDS	Chinese USA	Flash Point	164.8±11.7 °C
	Symbol	GHS06, GHS09	Signal Word	Danger

Use of 1,10-Phenanthroline

o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm[1].

Name	1,10-phenanthroline
Synonym	More Synonyms

Description	o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Guan NanMu, et al. Synergistic inhibition between o-phenanthroline and chloride ion on cold rolled steel corrosion in phosphoric acid. Materials Chemistry and Physics Volume 86, Issue 1, 15 July 2004, Pages 59-68.

Density	1.3±0.1 g/cm3
Boiling Point	365.1±15.0 °C at 760 mmHg
Melting Point	114-117 °C(lit.)
Molecular Formula	C₁₂H₈N₂
Molecular Weight	180.205
Flash Point	164.8±11.7 °C
Exact Mass	180.068741
PSA	25.78000
LogP	1.78
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.740
Storage condition	Refrigerator
Stability	Stable. Hygroscopic. Store under nitrogen. Incompatible with strong acids, strong oxidizing agents.
Water Solubility	slightly soluble

1,10-Phenanthroline MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SF8300000

CHEMICAL NAME :: 1,10-Phenanthroline

CAS REGISTRY NUMBER :: 66-71-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C12-H8-N2

MOLECULAR WEIGHT :: 180.22

WISWESSER LINE NOTATION :: T B666 CN NNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Kidney, Ureter, Bladder - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 30 mg/kg

SEX/DURATION :: female 8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Leukocyte

DOSE/DURATION :: 5 mg/L

REFERENCE :: ONCOBS Oncology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.21- 1967- Volume(issue)/page/year: 46,193,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82276 No. of Facilities: 1002 (estimated) No. of Industries: 12 No. of Occupations: 11 No. of Employees: 8324 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82276 No. of Facilities: 2265 (estimated) No. of Industries: 33 No. of Occupations: 35 No. of Employees: 40330 (estimated) No. of Female Employees: 2577 (estimated)

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301-H410
Precautionary Statements	P273-P301 + P310-P501
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic
Risk Phrases	R25;R50/53
Safety Phrases	S45-S60-S61
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	SF8437000
Packaging Group	III
Hazard Class	6.1
HS Code	29339990

Precursor 7
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DownStream 10
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HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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1,10-Phenanthroline

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ORTHOPHENANTHROLINE

EINECS 200-629-2

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o-Phenanthroline

β-Phenanthroline

1,10-Fenanthroline

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MFCD00011678

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phen

10-Phenanthroline

T B666 CN NNJ

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1,10-Phenanthroline
Price: Check
Purity: 99.0%
Delivery: 10 Day
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1,10-Phenanthroline
Price: ￥568.0/100g ￥178.0/25g
Purity: 97.0%
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: O-phenanthroline
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
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DC Chemicals Limited
China
Product Name: O-phenanthroline
Price: $100.0/100mg $200.0/250mg $400.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,10-Phenanthroline
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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1,10-Phenanthroline

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