Esfenvalerate

Modify Date: 2024-01-02 10:23:45

Esfenvalerate Structure
Esfenvalerate structure
Common Name Esfenvalerate
CAS Number 66230-04-4 Molecular Weight 419.900
Density 1.2±0.1 g/cm3 Boiling Point 538.9±50.0 °C at 760 mmHg
Molecular Formula C25H22ClNO3 Melting Point 59°C
MSDS Chinese USA Flash Point 279.7±30.1 °C
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger

 Use of Esfenvalerate


Esfenvalerate is one of the four isomers of the pyrethroid insecticide fenvalerate[1].

 Names

Name Esfenvalerate
Synonym More Synonyms

 Esfenvalerate Biological Activity

Description Esfenvalerate is one of the four isomers of the pyrethroid insecticide fenvalerate[1].
Related Catalog
In Vivo Esfenvalerate (0.1, 1, 7.5 or 15 mg/kg/day; gavage; from gestation day (GD) 13 to 19) shows clinical signs of neurotoxicity with 15 mg/kg/day[1].
References

[1]. Anne-Marie Saillenfait, et al. The Pyrethroid Insecticides Permethrin and Esfenvalerate Do Not Disrupt Testicular Steroidogenesis in the Rat Fetus. Toxicology. 2018 Dec 1;410:116-124.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 538.9±50.0 °C at 760 mmHg
Melting Point 59°C
Molecular Formula C25H22ClNO3
Molecular Weight 419.900
Flash Point 279.7±30.1 °C
Exact Mass 419.128815
PSA 59.32000
LogP 6.68
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.586

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CY1576367
CHEMICAL NAME :
Benzeneacetic acid, 4-chloro-alpha-(1-methylethyl)-, cyano (3-phenoxyphenyl)methyl ester, (S-(R*,R*))-
CAS REGISTRY NUMBER :
66230-04-4
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C25-H22-Cl-N-O3
MOLECULAR WEIGHT :
419.93

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
325 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C287,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C287,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C27,1991 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,309,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,309,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,309,1991

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301 + H331-H317-H410
Precautionary Statements P261-P273-P280-P301 + P310 + P330-P304 + P340 + P312-P403 + P233
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases R23/25;R43;R50/53
Safety Phrases S24-S36/37/39-S45-S60-S61
RIDADR UN 2811
RTECS CY1576367
Packaging Group III
Hazard Class 6.1(b)
HS Code 2926909090

 Customs

HS Code 2926909090
Summary HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles41

More Articles
Environmentally relevant mixing ratios in cumulative assessments: a study of the kinetics of pyrethroids and their ester cleavage metabolites in blood and brain; and the effect of a pyrethroid mixture on the motor activity of rats.

Toxicology 320 , 15-24, (2014)

National surveys of United States households and child care centers have demonstrated that pyrethroids are widely distributed in indoor habited dwellings and this suggests that co-exposure to multiple...

[Chemical toxicological identification of esfenvalerate].

Sud. Med. Ekspert. 55(3) , 37-41, (2012)

The optimal conditions for the isolation of esfenvalerate from the biological specimens have been determined. It was shown that this compound can be separated from the endogenous component of a biolog...

Pyrethroids in human breast milk: occurrence and nursing daily intake estimation.

Environ. Int. 47 , 17-22, (2012)

There is an assumption that pyrethroid pesticides are converted to non-toxic metabolites by hydrolysis in mammals. However, some recent works have shown their bioaccumulation in human breast milk coll...

 Synonyms

Sumi-α
(S-(R*,R*))-Cyano(3-phenoxyphenyl)methyl 4-chloro-2-(1-methylethyl)benzeneacetate
(S)-α-Cyano-3-phenoxybenzyl (S)-2-(4-chlorophenyl)-3-methylbutyrate
(S)-Cyano(3-phenoxyphenyl)methyl (2S)-2-(4-chlorophenyl)-3-methylbutanoate
Asana
Asana XL
Halmark
S,S-fenvalerate
Esfenvalerate
(S)-a-Cyano-3-phenoxybenzyl (S)-2-(4-chlorophenyl)-3-methylbutyrate
(αS)-α-cyano-3-phenoxybenzyl (2S)-2-(4-chlorophenyl)-3-methylbutyrate
MFCD00203302
Benzeneacetic acid, 4-chloro-α-(1-methylethyl)-, (S)-cyano(3-phenoxyphenyl)methyl ester, (αS)-
(S)-cyano(3-phenoxyphenyl)methyl (αS)-4-chloro-α-(1-methylethyl)benzeneacetate
Fenvalerate (S,S)-isomer
Top Suppliers:I want be here




Get all suppliers and price by the below link:

Esfenvalerate suppliers

Esfenvalerate price