methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate,hydrochloride

Modify Date: 2024-01-13 08:52:15

methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate,hydrochloride Structure
methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate,hydrochloride structure
Common Name methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate,hydrochloride
CAS Number 66634-44-4 Molecular Weight 390.90400
Density N/A Boiling Point N/A
Molecular Formula C21H27ClN2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate,hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C21H27ClN2O3
Molecular Weight 390.90400
Exact Mass 390.17100
PSA 65.56000
LogP 3.38700

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZG1025000
CHEMICAL NAME :
Yohimban-16-beta-carboxylic acid, 17-alpha-hydroxy-, methyl ester, hydrochloride
CAS REGISTRY NUMBER :
66634-44-4
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C21-H26-N2-O3.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 50,241,1935
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
158 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 146,1042,1952

 Synonyms

Prestwick_751
Rauhimbine
17|A-Hydroxyyohimban-16|A-carboxylic acid methyl ester
EINECS 266-430-8
17alpha-Hydroxyyohimban-16beta-carboxylic acid methyl ester
MFCD00064554
Chlorhydrate de corynanthine