Metazachlor

Modify Date: 2024-01-02 14:55:33

Metazachlor Structure
Metazachlor structure
Common Name Metazachlor
CAS Number 67129-08-2 Molecular Weight 277.74900
Density 1.19 g/cm3 Boiling Point 439.2ºC at 760 mmHg
Molecular Formula C14H16ClN3O Melting Point 74-78°C
MSDS Chinese USA Flash Point 2 °C
Symbol GHS07 GHS08 GHS09
GHS07, GHS08, GHS09
Signal Word Warning

 Use of Metazachlor


Metazachlor is a herbicide of the chloroacetamide class. Metazachlor is an inhibitor of the synthesis of long chain fatty acids and has an effect on cell division or tissue differentiation in the germinating and emerging weed target species[1].

 Names

Name metazachlor
Synonym More Synonyms

 Metazachlor Biological Activity

Description Metazachlor is a herbicide of the chloroacetamide class. Metazachlor is an inhibitor of the synthesis of long chain fatty acids and has an effect on cell division or tissue differentiation in the germinating and emerging weed target species[1].
Related Catalog
Target

IC50: synthesis of long chain fatty acids[1]

References

[1]. Christiane Wiemann, et al. Metazachlor: Mode of action analysis for rat liver tumour formation and human relevance. Toxicology. 2019 Oct 1;426:152282.

 Chemical & Physical Properties

Density 1.19 g/cm3
Boiling Point 439.2ºC at 760 mmHg
Melting Point 74-78°C
Molecular Formula C14H16ClN3O
Molecular Weight 277.74900
Flash Point 2 °C
Exact Mass 277.09800
PSA 38.13000
LogP 2.72940
Index of Refraction 1.586

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB5442000
CHEMICAL NAME :
Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmet hyl)-
CAS REGISTRY NUMBER :
67129-08-2
BEILSTEIN REFERENCE NO. :
0621550
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C14-H16-Cl-N3-O
MOLECULAR WEIGHT :
277.78
WISWESSER LINE NOTATION :
T5NNJ A1NV1GR B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C54,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>6810 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,560,1991

 Safety Information

Symbol GHS07 GHS08 GHS09
GHS07, GHS08, GHS09
Signal Word Warning
Hazard Statements H302-H351-H410
Precautionary Statements P273-P301 + P312 + P330-P391-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22
Safety Phrases S36-S26-S16
RIDADR UN 1648 3/PG 2
RTECS AB5442000

 Synthetic Route

~%

Metazachlor Structure

Metazachlor

CAS#:67129-08-2

Literature: WO2013/104478 A1, ; Page/Page column 18 ;

 Synonyms

bas479h
Metazachlor
Pree
MFCD00055509
EINECS 266-583-0
2-chloro-N-(pyrazol-1-ylmethyl)acet-2’,6’-xylidide
2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide
BUTISAN S
Butisan
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