α-cypermethrin

Modify Date: 2024-01-04 22:02:52

α-cypermethrin Structure
α-cypermethrin structure
Common Name α-cypermethrin
CAS Number 67375-30-8 Molecular Weight 416.297
Density 1.3±0.1 g/cm3 Boiling Point 511.3±50.0 °C at 760 mmHg
Molecular Formula C22H19Cl2NO3 Melting Point 78-81ºC
MSDS Chinese USA Flash Point 263.0±30.1 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

 Use of α-cypermethrin


Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is an effective insecticide against house flies[1].

 Names

Name (1S)-cis-(αR)-cypermethrin
Synonym More Synonyms

 α-cypermethrin Biological Activity

Description Alpha-Cypermethrin (FMC 45497; Fendona; WL 85871) is an effective insecticide against house flies[1].
Related Catalog
References

[1]. Abbas N, et al. Alpha-Cypermethrin Resistance in Musca domestica: Resistance Instability, Realized Heritability, Risk Assessment, and Insecticide Cross-Resistance. Insects. 2023 Feb 26;14(3):233.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 511.3±50.0 °C at 760 mmHg
Melting Point 78-81ºC
Molecular Formula C22H19Cl2NO3
Molecular Weight 416.297
Flash Point 263.0±30.1 °C
Exact Mass 415.074188
PSA 118.64000
LogP 6.27
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.622
Stability Stable. Incompatible with strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GZ1251400
CHEMICAL NAME :
Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl) methyl ester, (1-alpha(S*),3-alpha)-(+-)-
CAS REGISTRY NUMBER :
67375-30-8
LAST UPDATED :
199801
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C22-H19-Cl2-N-O3
MOLECULAR WEIGHT :
416.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
79 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1900 mg/m3/4H
TOXIC EFFECTS :
Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
336 mg/kg/28D-I
TOXIC EFFECTS :
Brain and Coverings - changes in brain weight Endocrine - changes in spleen weight Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TEST SYSTEM :
Non-mammalian species
DOSE/DURATION :
5 ppb
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 298,25,1992

 Safety Information

Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H301-H335-H373-H410
Precautionary Statements P273-P301 + P310 + P330-P391-P501
Hazard Codes T:Toxic
Risk Phrases R25;R37;R48/22;R50/53
Safety Phrases S36/37/39-S45-S60-S61
RIDADR UN 2811
WGK Germany 3
RTECS GZ1250000
Packaging Group III
Hazard Class 6.1(b)

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 Synonyms

Cyano(3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid cyano(3-phenoxyphenyl)methyl ester
Cnn52
α-cypermethrin
(1S,3S)-(R)-Cyano(3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
rac-(R)-cyano(3-phenoxyphenyl)methyl (1S,3S)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
UNII:1TR49121NP
(RS)-α-Cyano-3-phenoxybenzyl (1RS)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
(R)-cyano(3-phenoxyphenyl)methyl (1S,3S)-rel-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
alphamethrin
alpha-cypermethrin
Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl)methyl ester
(R)-Cyano(3-phenoxyphenyl)methyl (1S,3S)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate - (S)-cyano(3-phenoxyphenyl)methyl (1R,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate (1:1)
(1S)-cis-(alphaR)-cypermethrin
Kefil Super
(RS)-α-cyano-3-phenoxybenzyl (1RS)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, cyano(3-phenoxyphenyl)methyl ester, (±)-
Cypermethrin
(RS)-α-cyano-3-phenoxybenzyl (1RS,3RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
cypermethrin [ANSI]
Cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
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