Bromo-PEG5-bromide
Bromo-PEG5-bromide structure
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Common Name | Bromo-PEG5-bromide | ||
|---|---|---|---|---|
| CAS Number | 67705-77-5 | Molecular Weight | 408.12400 | |
| Density | 1.433g/cm3 | Boiling Point | 413.195ºC at 760 mmHg | |
| Molecular Formula | C12H24Br2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 170.724ºC | |
Use of Bromo-PEG5-bromideBromo-PEG5-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Summary: 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide (Bromo-PEG5-bromide, CAS 67705-77-5), with molecular formula C12H24Br2O5 and molecular weight 408.12400, is suitable for nucleophilic substitution reactions. The hydrophilic PEG spacer increases its solubility in aqueous media. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Bromo-PEG5-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.433g/cm3 |
|---|---|
| Boiling Point | 413.195ºC at 760 mmHg |
| Molecular Formula | C12H24Br2O5 |
| Molecular Weight | 408.12400 |
| Flash Point | 170.724ºC |
| Exact Mass | 405.99900 |
| PSA | 46.15000 |
| LogP | 1.85920 |
| Index of Refraction | 1.486 |
| InChIKey | LACSKPODWQXGSB-UHFFFAOYSA-N |
| SMILES | BrCCOCCOCCOCCOCCOCCBr |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~86%
Bromo-PEG5-bromide CAS#:67705-77-5 |
| Literature: Biron, Eric; Otis, Francois; Meillon, Jean-Christophe; Robitaille, Martin; Lamothe, Julie; Van Hove, Patrick; Cormier, Marie-Eve; Voyer, Normand Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 6 p. 1279 - 1290 |
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~%
Bromo-PEG5-bromide CAS#:67705-77-5 |
| Literature: Rabouin, Daniel; Perron, Valerie; N'Zemba, Blaise; C.-Gaudreault, Rene; Berube, Gervais Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 557 - 560 Title/Abstract Full Text View citing articles Show Details Berube, Gervais; Rabouin, Daniel; Perron, Valerie; N'Zemba, Blaise; Gaudreault, Rene-C.; Parent, Sophie; Asselin, Eric Steroids, 2006 , vol. 71, # 10 p. 911 - 921 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 2 | |
|---|---|
| DownStream 0 | |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 1-[2-(2-bromoethoxy)ethoxy]-2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethane |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide? |
| A: Polar surface area (PSA) of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide is 46.15000. |
| Q: What English synonyms does 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide have? |
| A: English synonyms of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide: 1-[2-(2-bromoethoxy)ethoxy]-2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethane. |
| Q: What is the CAS number of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide? |
| A: CAS number of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide is 67705-77-5. |
| Q: What are the uses of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide? |
| A: Main uses of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide: Bromo-PEG5-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Q: What is the English name of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide? |
| A: The English name of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide is 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide. |
| Q: What is the molecular weight of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide? |
| A: Molecular weight of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide is 408.12400. |
| Q: What is the InChIKey of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide? |
| A: InChIKey of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide is LACSKPODWQXGSB-UHFFFAOYSA-N. |
| Q: What is the boiling point of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide? |
| A: Boiling point of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide is 413.195ºC at 760 mmHg. |
| Q: What is the molecular formula of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide? |
| A: Molecular formula of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide is C12H24Br2O5. |
| Q: What is the SMILES notation of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide? |
| A: SMILES notation of 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl Bis-bromide is BrCCOCCOCCOCCOCCOCCBr. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |