5β-Dihydrocortisone

Modify Date: 2024-02-02 17:47:59

5β-Dihydrocortisone Structure
5β-Dihydrocortisone structure
Common Name 5β-Dihydrocortisone
CAS Number 68-54-2 Molecular Weight 362.46000
Density N/A Boiling Point N/A
Molecular Formula C21H30O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5β-Dihydrocortisone


5β-Dihydrocortisone is a sterol metabolite of cortisone by 5β-reductase (AKR1D1) in liver[1].

 Names

Name 17,21-dihydroxy-5β-pregnane-3,11,20-trione
Synonym More Synonyms

 5β-Dihydrocortisone Biological Activity

Description 5β-Dihydrocortisone is a sterol metabolite of cortisone by 5β-reductase (AKR1D1) in liver[1].
Related Catalog
References

[1]. Nikolaos Nikolaou, et al. AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells. J Steroid Biochem Mol Biol

 Chemical & Physical Properties

Molecular Formula C21H30O5
Molecular Weight 362.46000
Exact Mass 362.20900
PSA 91.67000
LogP 2.06970

 Synthetic Route

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5β-Dihydrocortisone Structure

5β-Dihydrocortisone

CAS#:68-54-2

Literature: Kritchevsky et al. Journal of the American Chemical Society, 1952 ,  vol. 74, p. 483,485            

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

5β-dihydrocortisone
5BETA-PREGNAN-17ALPHA,21-DIOL-3,11,20-TRIONE
5Beta-Dihydrocortisone
17,21-dihydroxy-5beta-pregnane-3,11,20-trione
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Price: ¥550/10 mM * 1 mL in DMSO

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