2,5-Cyclohexadiene-1,4-dione,2,3,5-tri-1-aziridinyl
Modify Date: 2026-07-25 14:33:47
2,5-Cyclohexadiene-1,4-dione,2,3,5-tri-1-aziridinyl structure
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Common Name | 2,5-Cyclohexadiene-1,4-dione,2,3,5-tri-1-aziridinyl | ||
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| CAS Number | 68-76-8 | Molecular Weight | 231.25100 | |
| Density | 1.727g/cm3 | Boiling Point | 376.5ºC at 760 mmHg | |
| Molecular Formula | C12H13N3O2 | Melting Point | 162.5-163ºC | |
| MSDS | N/A | Flash Point | 175.1ºC | |
Use of 2,5-Cyclohexadiene-1,4-dione,2,3,5-tri-1-aziridinylTrenimon is a compound with anti-cancer effects. Trenimon shows mutagenic actions in many species by inducing point and chromosomal mutations, sister-chromatid exchanges, recombination phenomena and phage induction. Trenimon can be used for the research of cancer[1][2][3][4]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | triaziquone |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Trenimon is a compound with anti-cancer effects. Trenimon shows mutagenic actions in many species by inducing point and chromosomal mutations, sister-chromatid exchanges, recombination phenomena and phage induction. Trenimon can be used for the research of cancer[1][2][3][4]. |
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| Related Catalog | |
| In Vitro | Trenimon (0.17 mM) penetrates readily into mouse lymphoma cells in vitro[1]. Trenimon (0.17 nM; 5 min-16 h) time-denpendently reduces the priming activity of DNA[2]. Trenimon (1 nM-10 μM; 10-20 min) leds HeLa cells death after 2 weeks with a dose of 10 μM and dose-dependently suppresses mitosis in cells[3]. |
| In Vivo | Trenimon (0.25 mg/kg; i.p. once) rapidly depresseas of the cellular elements of the peripheral blood (granulocytes, lymphocytes, reticulocytes, platelets and erythrocytes), and reduces the cell number of bone marrow[4]. Trenimon (0.03 mg/kg; i.v. once per week for 52 weeks) shows an cancerogenic effect in vivo[4]. Animal Model: BR 46 male rats[4] Dosage: 0.03 mg/kg Administration: Intravenous injection; 0.03 mg/kg once per week for 52 weeks Result: Showed an cancerogenic effect and 24% animals developed malign tumors, and showed a induction time of the tumors is 16 months. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.727g/cm3 |
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| Boiling Point | 376.5ºC at 760 mmHg |
| Melting Point | 162.5-163ºC |
| Molecular Formula | C12H13N3O2 |
| Molecular Weight | 231.25100 |
| Flash Point | 175.1ºC |
| Exact Mass | 231.10100 |
| PSA | 43.17000 |
| Index of Refraction | 1.846 |
| InChIKey | PXSOHRWMIRDKMP-UHFFFAOYSA-N |
| SMILES | O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1 |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| RIDADR | UN 3249 |
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| Packaging Group | II |
| Hazard Class | 6.1(a) |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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2,5-Cyclohexadi... CAS#:68-76-8 |
| Literature: Gauss Chemische Berichte, 1958 , vol. 91, p. 2216,2222 |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Trenimon |
| Triethyleneiminobenzoquinone |
| Riker 601 |
| Oncoredox |
| 2,3,5-tris(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione |
| Triaziquinone |
| Prenimon |
| Treninon |
| 2.3.5-Tris-aziridino-benzo-1.4-chinon |
| Oncovedex |
| Triaziquon |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of triaziquone? |
| A: Main uses of triaziquone: Trenimon is a compound with anti-cancer effects. Trenimon shows mutagenic actions in many species by inducing point and chromosomal mutations, sister-chromatid exchanges, recombination phenomena and phage induction. Trenimon can be used for the research of cancer[1][2][3][4]. |
| Q: What is the molecular weight of triaziquone? |
| A: Molecular weight of triaziquone is 231.25100. |
| Q: What is the CAS number of triaziquone? |
| A: CAS number of triaziquone is 68-76-8. |
| Q: What is the boiling point of triaziquone? |
| A: Boiling point of triaziquone is 376.5ºC at 760 mmHg. |
| Q: What is the polar surface area (PSA) of triaziquone? |
| A: Polar surface area (PSA) of triaziquone is 43.17000. |
| Q: What is the SMILES notation of triaziquone? |
| A: SMILES notation of triaziquone is O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1. |
| Q: What is the InChIKey of triaziquone? |
| A: InChIKey of triaziquone is PXSOHRWMIRDKMP-UHFFFAOYSA-N. |
| Q: What is the English name of triaziquone? |
| A: The English name of triaziquone is triaziquone. |
| Q: What English synonyms does triaziquone have? |
| A: English synonyms of triaziquone: Trenimon, Triethyleneiminobenzoquinone, Riker 601, Oncoredox, 2,3,5-tris(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione, Triaziquinone, Prenimon, Treninon, 2.3.5-Tris-aziridino-benzo-1.4-chinon, Oncovedex, Triaziquon. |
| Q: What is the melting point of triaziquone? |
| A: Melting point of triaziquone is 162.5-163ºC. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |