3-nitro-2-pyridinesulfenyl chloride

Modify Date: 2024-01-03 12:21:36

3-nitro-2-pyridinesulfenyl chloride Structure
3-nitro-2-pyridinesulfenyl chloride structure
Common Name 3-nitro-2-pyridinesulfenyl chloride
CAS Number 68206-45-1 Molecular Weight 190.60800
Density 1.58g/cm3 Boiling Point 376.8ºC at 760mmHg
Molecular Formula C5H3ClN2O2S Melting Point 205ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 181.7ºC
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name (3-nitropyridin-2-yl) thiohypochlorite
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.58g/cm3
Boiling Point 376.8ºC at 760mmHg
Melting Point 205ºC (dec.)(lit.)
Molecular Formula C5H3ClN2O2S
Molecular Weight 190.60800
Flash Point 181.7ºC
Exact Mass 189.96000
PSA 84.01000
LogP 2.75890
Storage condition 2-8°C
Water Solubility dichloromethane: soluble(lit.)

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C
Risk Phrases R34
Safety Phrases 26-27-36/37/39-45
RIDADR UN 3261 8/PG 2
WGK Germany 3

 Articles8

More Articles
Synthesis of disulfide-bridged fragments of omega-conotoxins GVIA and MVIIA. Use of Npys as a protecting/activating group for cysteine in Fmoc syntheses.

Int. J. Pept. Protein Res. 43(4) , 363-6, (1994)

The 3-nitro-2-pyridinesulphenyl (Npys) moiety is finding increasing utility as a protecting-activating group for cysteine, particularly in the synthesis of cyclic and unsymmetrical disulfides using th...

Synthesis and stability of 3-nitro-2-pyridinesulfenyl chloride (NpysCl).

Int. J. Pept. Protein Res. 42(2) , 159-64, (1993)

3-Nitro-2-pyridinesulfenyl chloride (NpysCl) is the starting material for the synthesis of N-, O- and S-Npys-protected amino acids. Two efficient, novel synthetic routes to NpysCl are described. The s...

Discriminative affinity labelling of opioid receptors by enkephalin and morphiceptin analogues containing 3-nitro-2-pyridinesulphenyl-activated thiol residues.

J. Chromatogr. A. 597(1-2) , 425-8, (1992)

The thiol groups of leucinthiol, cysteamine and cysteine incorporated into opioid peptides enkephalin and morphiceptin were activated by the 3-nitro-2-pyridinesulphenyl (Npys) group to form mixed disu...

 Synonyms

3-Nitro-2-pyridinesulfenyl chloride
3-nitropyridine-2-sulfenyl chloride
3-nitro-2-pyridinylsulfenyl chloride
Pyridine,2-chlorothio-3-nitro
2-Pyridinesulfenyl chloride,3-nitro
3-nitropyridinesulfenyl chloride
3-nitro-pyridin-2-ylsulfenyl chloride
Npys-Cl
Npys
MFCD00274609
3-Nitro-2-pyridinesulfenyl