cremophor (r) a25

Modify Date: 2024-01-07 22:28:27

cremophor (r) a25 Structure
cremophor (r) a25 structure
Common Name cremophor (r) a25
CAS Number 68439-49-6 Molecular Weight 144.172
Density 1.1±0.1 g/cm3 Boiling Point 223.6±35.0 °C at 760 mmHg
Molecular Formula C6H12N2O2 Melting Point N/A
MSDS Chinese USA Flash Point 89.0±25.9 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of cremophor (r) a25


Polyoxyl 20 Cetostearyl Ether can be used as an excipient, such as Emulsifier and solubilizer for emulsions and creams, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

 Names

Name Methyl 2-piperazinecarboxylate
Synonym More Synonyms

 cremophor (r) a25 Biological Activity

Description Polyoxyl 20 Cetostearyl Ether can be used as an excipient, such as Emulsifier and solubilizer for emulsions and creams, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].
Related Catalog
References

[1]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 223.6±35.0 °C at 760 mmHg
Molecular Formula C6H12N2O2
Molecular Weight 144.172
Flash Point 89.0±25.9 °C
Exact Mass 144.089874
LogP -1.00
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.443
Water Solubility H2O: 1 g/10 mL, clear, colorless

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H315-H319-H400
Precautionary Statements P273-P280-P301 + P312 + P330-P305 + P351 + P338-P337 + P313-P391
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes N
Risk Phrases 50/53
Safety Phrases 60-61
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS AZ0883332

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 Synonyms

Methyl 2-piperazinecarboxylate
2-Piperazinecarboxylic acid, methyl ester
2-Piperazinecarboxylic acid methyl ester
MFCD07772085