N-Boc-m-phenylenediamine

Modify Date: 2024-01-04 11:56:39

N-Boc-m-phenylenediamine Structure
N-Boc-m-phenylenediamine structure
Common Name N-Boc-m-phenylenediamine
CAS Number 68621-88-5 Molecular Weight 208.257
Density 1.2±0.1 g/cm3 Boiling Point 295.1±23.0 °C at 760 mmHg
Molecular Formula C11H16N2O2 Melting Point N/A
MSDS Chinese USA Flash Point 132.3±22.6 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name tert-butyl N-(3-aminophenyl)carbamate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 295.1±23.0 °C at 760 mmHg
Molecular Formula C11H16N2O2
Molecular Weight 208.257
Flash Point 132.3±22.6 °C
Exact Mass 208.121185
PSA 64.35000
LogP 1.86
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.583

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22
RIDADR NONH for all modes of transport
HS Code 2924299090

 Synthetic Route

~98%

N-Boc-m-phenylenediamine Structure

N-Boc-m-phenyle...

CAS#:68621-88-5

Literature: McDonald, Iain M.; Austin, Carol; Buck, Ildiko M.; Dunstone, David J.; Griffin, Eric; Harper, Elaine A.; Hull, Robert A. D.; Kalindjian, S. Barret; Linney, Ian D.; Low, Caroline M. R.; Pether, Michael J.; Spencer, John; Wright, Paul T.; Adatia, Trushar; Bashall, Alan Journal of Medicinal Chemistry, 2006 , vol. 49, # 7 p. 2253 - 2261

~92%

N-Boc-m-phenylenediamine Structure

N-Boc-m-phenyle...

CAS#:68621-88-5

Literature: PROMETIC BIOSCIENCES INC. Patent: WO2006/136005 A1, 2006 ; Location in patent: Page/Page column 22; 23 ;

~64%

N-Boc-m-phenylenediamine Structure

N-Boc-m-phenyle...

CAS#:68621-88-5

Literature: Seto, Christopher T.; Whitesides, George M. Journal of the American Chemical Society, 1993 , vol. 115, # 3 p. 905 - 916

~%

N-Boc-m-phenylenediamine Structure

N-Boc-m-phenyle...

CAS#:68621-88-5

Literature: Journal of Medicinal Chemistry, , vol. 45, # 4 p. 944 - 954

~91%

N-Boc-m-phenylenediamine Structure

N-Boc-m-phenyle...

CAS#:68621-88-5

Literature: Mullick, Dibakar; Anjanappa, Prakash; Selvakumar, Kumaravel; Ruckmani, Kandasamy; Sivakumar, Manickam Tetrahedron Letters, 2010 , vol. 51, # 46 p. 5984 - 5987

~%

N-Boc-m-phenylenediamine Structure

N-Boc-m-phenyle...

CAS#:68621-88-5

Literature: Journal of Medicinal Chemistry, , vol. 45, # 4 p. 944 - 954

~%

N-Boc-m-phenylenediamine Structure

N-Boc-m-phenyle...

CAS#:68621-88-5

Literature: Journal of Medicinal Chemistry, , vol. 49, # 7 p. 2253 - 2261

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles3

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Macrocyclic receptor for pertechnetate and perrhenate anions.

Org. Biomol. Chem. 9(21) , 7358-64, (2011)

The design and synthesis of a neutral macrocyclic host that is capable of perrhenate and pertechnetate recognition is described. The anion affinities and underlying coordination modes were estimated b...

Pyrimido [4,5-d] pyrimidin-4(1H)-one Derivatives as Selective Inhibitors of EGFR Threonine790 to Methionine790 (T790M) Mutants. Xu T, et al.

Angew. Chem. Weinheim Bergstr. Ger. 125(32) , 8545-8548, (2013)

Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting epidermal growth factor receptor threonine790? methionine790 mutant. Chang S, et al.

J. Med. Chem. 55(6) , 2711-2723, (2012)

 Synonyms

T-butyl-3-aminophenylcarbamate
tert-Butyl (3-aminophenyl)carbamate
(3-Aminophenyl)carbamic acid tert-butyl ester
N-BOC-meta-phenylenediamine
(3-aminophenyl)carbamic acid,1,1-dimethylethyl ester
3-(N-tert-butoxycarbonylamino)aniline
2-Methyl-2-propanyl (3-aminophenyl)carbamate
N-Boc-m-phenylenediamine
3-(tert-Butoxycarbonylamino)aniline
tert-butyl 3-aminophenylcarbamate
Carbamic acid, N-(3-aminophenyl)-, 1,1-dimethylethyl ester
N-Boc-amino-3-aniline
N-Boc-1,3-diaminobenzene