UNII:EIL57224QR

Modify Date: 2024-01-08 11:32:09

UNII:EIL57224QR Structure
UNII:EIL57224QR structure
Common Name UNII:EIL57224QR
CAS Number 6865-14-1 Molecular Weight 436.069
Density N/A Boiling Point N/A
Molecular Formula C23H46ClNO4 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of UNII:EIL57224QR


Palmitoylcarnitine chloride is a fatty acid-derived mitochondrial substrate, and selectively decreases cell survival in colorectal and prostate cancer cells by affecting on pro-inflammatory pathways, Ca2+ influx, and DHT-like effects[1].

 Names

Name Palmitoyl-DL-carnitine chloride
Synonym More Synonyms

 UNII:EIL57224QR Biological Activity

Description Palmitoylcarnitine chloride is a fatty acid-derived mitochondrial substrate, and selectively decreases cell survival in colorectal and prostate cancer cells by affecting on pro-inflammatory pathways, Ca2+ influx, and DHT-like effects[1].
Related Catalog
References

[1]. Al-Bakheit A, et al. Accumulation of Palmitoylcarnitine and Its Effect on Pro-Inflammatory Pathways and Calcium Influx in Prostate Cancer. Prostate. 2016 Oct;76(14):1326-37.

 Chemical & Physical Properties

Molecular Formula C23H46ClNO4
Molecular Weight 436.069
Exact Mass 435.311523
PSA 63.60000
LogP 2.56440
Storage condition 20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
HS Code 2923900090

 Synthetic Route

~%

UNII:EIL57224QR Structure

UNII:EIL57224QR

CAS#:6865-14-1

Literature: Hoppe-Seyler's Zeitschrift fuer physiologische Chemie, , vol. 343, # 4 p. 231 - 239

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2923900090
Summary 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles8

More Articles
Modulation by palmitoylcarnitine of protein kinase C activation.

Cancer Res. 47 , 6537-6542, (1987)

Palmitoylcarnitine, a reported protein kinase C inhibitor, enhanced the phorbol ester dependency of the enzyme, augmenting protein kinase C activity in the presence of phorbol esters such as phorbol 1...

Palmitoyl-DL-carnitine has calcium-dependent effects on cultured neurones from rat dorsal root ganglia.

Br. J. Pharmacol. 107 , 1192-1197, (1992)

1. The effects of palmitoyl-DL-carnitine (0.01 to 1 mM) on whole cell voltage-activated calcium channel currents carried by calcium or barium and Ca(2+)-activated chloride currents were studied in cul...

Palmitoyl-L-carnitine modifies the function of vascular endothelium.

Cardiovasc. Res. 28 , 129-134, (1994)

Palmitoyl-L-carnitine, which accumulates in ischaemic myocardium, may influence the function of vascular endothelium in the ischaemic area. The aim of the study was therefore to examine the effect of ...

 Synonyms

Palmitoyl-L-carnitine chloride
3-carboxy-n,n,n-trimethyl-2-(palmitoyloxy)propan-1-aminium chloride
UNII:EIL57224QR
1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-[(1-oxohexadecyl)oxy]-, chloride (1:1)
3-Carboxy-N,N,N-trimethyl-2-(palmitoyloxy)-1-propanaminium chloride
(±)-Palmitoylcarnitine chloride