DTNB

Modify Date: 2025-08-20 18:41:37

DTNB structure	Common Name	DTNB
	CAS Number	69-78-3	Molecular Weight	396.352
	Density	1.8±0.1 g/cm3	Boiling Point	671.9±55.0 °C at 760 mmHg
	Molecular Formula	C₁₄H₈N₂O₈S₂	Melting Point	240-245 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	360.1±31.5 °C

Use of DTNB

DTNB(Ellman’s Reag) is a chemical used to quantify the number or concentration of thiol groups in a sample; can be used for measuring low-molecular mass thiols such as glutathione in both pure solutions and biological samples, such as blood.

Name	dithionitrobenzoic acid
Synonym	More Synonyms

Description	DTNB(Ellman’s Reag) is a chemical used to quantify the number or concentration of thiol groups in a sample; can be used for measuring low-molecular mass thiols such as glutathione in both pure solutions and biological samples, such as blood.
Related Catalog	Signaling Pathways >> Others >> Others Biochemical Assay Reagents Research Areas >> Others

Density	1.8±0.1 g/cm3
Boiling Point	671.9±55.0 °C at 760 mmHg
Melting Point	240-245 °C (dec.)(lit.)
Molecular Formula	C₁₄H₈N₂O₈S₂
Molecular Weight	396.352
Flash Point	360.1±31.5 °C
Exact Mass	395.972198
PSA	216.84000
LogP	3.97
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.769
Storage condition	Store at RT.
Stability	Stable. Incompatible with strong bases, strong oxidizing agents.

DTNB MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG9650000

CHEMICAL NAME :: Benzoic acid, 3,3'-dithiobis(6-nitro-

CAS REGISTRY NUMBER :: 69-78-3

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H8-N2-O8-S2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2080 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,284,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7018 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 197 (estimated) No. of Female Employees: 145 (estimated)

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DG9650000
HS Code	29309070

Precursor 0
DownStream 7
CAS#:629-45-8 5,6-Dithiadecane CAS#:18430-02-9 2-nitro-5-merca... CAS#:30211-77-9 2-Nitro-5-thioc... CAS#:15139-21-6 TNB
CAS#:71899-86-0 5-(2-Aminoethyl... CAS#:822-27-5 Disulfide, dioctyl CAS#:5586-15-2 Disulfide,1,2-d...

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Disturbed Hsp70 and Hsp27 expression and thiol redox status in porcine kidney PK15 cells provoked by individual and combined ochratoxin A and citrinin treatments.

Food Chem. Toxicol. 71 , 97-105, (2014)

The aim of this study was to explore the oxidative properties of ochratoxin A (OTA) and citrinin (CTN) as a possible underlying mechanism of their individual and/or combined cytotoxicity. Metabolic ac...

Metabolic and tissue-specific regulation of acyl-CoA metabolism.

PLoS ONE 10(3) , e0116587, (2015)

Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ligation of a fatty acid to Coenzyme A mediated by a large family of acyl-CoA synthetases (ACS). Conversely,...

Mitochondrial NADP(+)-dependent isocitrate dehydrogenase knockdown inhibits tumorigenicity of melanoma cells.

Biochem. Biophys. Res. Commun. 451(2) , 246-51, (2014)

The potent cytotoxicity of reactive oxygen species (ROS) can cause various diseases but may also serve as a powerful weapon capable of destroying cancer cells. Although the balance between generation ...

3-Carboxy-4-nitrophenyl disulfide

EINECS 200-714-4

3,3'-Disulfanediylbis(6-nitrobenzoic acid)

Benzoic acid, 3,3'-dithiobis[6-nitro-

Ellman Reagent

MFCD00007140

5,5'-dithiobis-(2-nitrobenzoic acid)

5,5'-DITHIOBIS(2-NITROBENZOIC ACID)

5,5'-Dithobis(2-Nitrobenzoic Acid)

5,5-Dithiobis(2-nitrobenzoic acid)

5,5′-Dithiobis(2-nitrobenzoic acid)

UNII:9BZQ3U62JX

DTNB

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: DTNB
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: DTNB
Price: ￥178.0/5g ￥668.0/25g
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: DTNB
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-Carboxy-4-nitrophenyl disulfide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: DTNB
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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DTNB suppliers

Price: $66/10mM*1mLinDMSO

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DTNB

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Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.