Inh2-B1

Modify Date: 2023-01-15 18:18:44

Inh2-B1 Structure
Inh2-B1 structure
Common Name Inh2-B1
CAS Number 690216-38-7 Molecular Weight 411.45
Density N/A Boiling Point N/A
Molecular Formula C19H13N3O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Inh2-B1


Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain; exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge; down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA.

 Names

Name Inh2-B1

 Inh2-B1 Biological Activity

Description Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain; exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge; down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA.
References References 1. Kant S, et al. Sci Rep. 2017 Jul 11;7(1):5067. View Related Products by Target Bacterial

 Chemical & Physical Properties

Molecular Formula C19H13N3O4S2
Molecular Weight 411.45