690216-38-7
690216-38-7 structure
- Name: Inh2-B1
- Chemical Name: Inh2-B1
- CAS Number: 690216-38-7
- Molecular Formula: C19H13N3O4S2
- Molecular Weight: 411.45
- Create Date: 2020-01-20 07:54:56
- Modify Date: 2023-01-15 18:18:44
-
Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain; exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge; down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA.
| Name | Inh2-B1 |
|---|
| Description | Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain; exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge; down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA. |
|---|---|
| References | References 1. Kant S, et al. Sci Rep. 2017 Jul 11;7(1):5067. View Related Products by Target Bacterial |
| Molecular Formula | C19H13N3O4S2 |
|---|---|
| Molecular Weight | 411.45 |