SABA1

Modify Date: 2024-01-13 22:57:52

SABA1 structure	Common Name	SABA1
	CAS Number	690681-65-3	Molecular Weight	458.91
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₉ClN₂O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SABA1

SABA1 possesses antibacterial properties against Pseudomonas aeruginosa and Escherichia coli, with an IC50 of 4.0 µM against E. coli ACC[1].

Name	SABA1

Description	SABA1 possesses antibacterial properties against Pseudomonas aeruginosa and Escherichia coli, with an IC50 of 4.0 µM against E. coli ACC[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	SABA1 inhibits BC via an atypical mechanism. It binds in the biotin binding site in the presence of ADP and represents a potentially antibiotic used to combat the antibacterial resistance crisis[1].
References	[1]. Matthew K Craft, et al. Mechanism of biotin carboxylase inhibition by ethyl 4-[[2-chloro-5-(phenylcarbamoyl)phenyl]sulphonylamino]benzoate. J Enzyme Inhib Med Chem. 2022 Dec;37(1):100-108.

Molecular Formula	C₂₂H₁₉ClN₂O₅S
Molecular Weight	458.91

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