(±)-Malic Acid

Modify Date: 2024-01-02 16:05:46

(±)-Malic Acid Structure
(±)-Malic Acid structure
 Common Name (±)-Malic Acid
CAS Number 6915-15-7 Molecular Weight 134.087
Density 1.6±0.1 g/cm3 Boiling Point 306.4±27.0 °C at 760 mmHg
Molecular Formula C4H6O5 Melting Point 131-133ºC(lit.)
MSDS Chinese USA Flash Point 153.4±20.2 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of (±)-Malic Acid


Malic acid is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods.

 Names

Name malic acid
Synonym More Synonyms

 (±)-Malic Acid Biological Activity

Description Malic acid is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Dai Z, et al. Current advance in biological production of malic acid using wild type and metabolic engineered strains. Bioresour Technol. 2018 Jun;258:345-353.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 306.4±27.0 °C at 760 mmHg
Melting Point 131-133ºC(lit.)
Molecular Formula C4H6O5
Molecular Weight 134.087
Flash Point 153.4±20.2 °C
Exact Mass 134.021530
PSA 94.83000
LogP -1.26
Vapour density 4.6 (vs air)
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.529
Storage condition 2-8°C
Water Solubility methanol: 0.1 g/mL, clear, colorless | 558 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ON7175000
CHEMICAL NAME :
Malic acid
CAS REGISTRY NUMBER :
6915-15-7
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C4-H6-O5
MOLECULAR WEIGHT :
134.10
WISWESSER LINE NOTATION :
QVYQ1VQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,657,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,657,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4937,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: #82-0458
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4937,1982 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1766 No. of Facilities: 1278 (estimated) No. of Industries: 11 No. of Occupations: 21 No. of Employees: 8629 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1766 No. of Facilities: 3524 (estimated) No. of Industries: 44 No. of Occupations: 46 No. of Employees: 80674 (estimated) No. of Female Employees: 51609 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P280-P305 + P351 + P338-P337 + P313
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS ON7175000
HS Code 2918990090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles85

More Articles
Urinary metabolic fingerprinting of mice with diet-induced metabolic derangements by parallel dual secondary column-dual detection two-dimensional comprehensive gas chromatography.

J. Chromatogr. A. 1361 , 265-76, (2014)

This study investigates the potential of a parallel dual secondary column-dual detection two-dimensional comprehensive GC platform (GC×2GC-MS/FID) for metabolic profiling and fingerprinting of mouse u...

Ultrasonication as a potential tool to predict solute crystallization in freeze-concentrates.

Pharm. Res. 31(6) , 1512-24, (2014)

We hypothesize that ultrasonication can accelerate solute crystallization in freeze-concentrates. Our objective is to demonstrate ultrasonication as a potential predictive tool for evaluating physical...

A metabolic-based approach to improve xylose utilization for fumaric acid production from acid pretreated wheat bran by Rhizopus oryzae.

Bioresour. Technol. 180 , 119-27, (2015)

In this work, wheat bran (WB) was utilized as feedstock to synthesize fumaric acid by Rhizopus oryzae. Firstly, the pretreatment process of WB by dilute sulfuric acid hydrolysis undertaken at 100°C fo...

 Synonyms

hydroxy-butanedioic acid
MFCD00064212
R,S(±)-Malic acid
Butanedioic acid, hydroxy-
alpha-Hydroxysuccinic acid
(±)-1-Hydroxy-1,2-ethanedicarboxylic Acid
UNII:817L1N4CKP
Butanedioic acid, 2-hydroxy-
Hydroxybutandisaeure
alpha-hydroxysuccinicacid
MALIC ACID, (DL)
hydroxysuccinic acid
DL(+/-)-MALIC ACID
R,S-Malic acid
2-hydroxybutane-1,4-dioic acid
EINECS 210-514-9
2-hydroxybutanedioic acid
2-Hydroxysuccinic Acid
a-Hydroxysuccinic Acid
Malic acid
Malic acid, dl-
DL-MALIC ACID
2-Hydroxy-succinic acid
DL-Hydroxybutanedioic acid
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Chemsrc provides (±)-Malic Acid(CAS#:6915-15-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of (±)-Malic Acid are included as well.>> amp version: (±)-Malic Acid

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