(S)-(+)-4-Amino-3-hydroxybutyric acid structure
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Common Name | (S)-(+)-4-Amino-3-hydroxybutyric acid | ||
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CAS Number | 7013-05-0 | Molecular Weight | 119.119 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 374.5±32.0 °C at 760 mmHg | |
Molecular Formula | C4H9NO3 | Melting Point | 207-212ºC | |
MSDS | Chinese USA | Flash Point | 180.3±25.1 °C |
Use of (S)-(+)-4-Amino-3-hydroxybutyric acidGABOB, also known as γ-Amino-β-hydroxybutyric acid, β-hydroxy-γ-aminobutyric acid, β-hydroxy-GABA, is an anticonvulsant which is used for the treatment of epilepsy in Europe, Japan, and Mexico. It is also an endogenous active metabolite and analogue of the neurotransmitter γ-aminobutyric acid (GABA), and for this reason, may function as a neurotransmitter itself. |
Name | (3S)-4-amino-3-hydroxybutanoic acid |
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Synonym | More Synonyms |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 374.5±32.0 °C at 760 mmHg |
Melting Point | 207-212ºC |
Molecular Formula | C4H9NO3 |
Molecular Weight | 119.119 |
Flash Point | 180.3±25.1 °C |
Exact Mass | 119.058243 |
PSA | 83.55000 |
LogP | -1.73 |
Vapour Pressure | 0.0±1.9 mmHg at 25°C |
Index of Refraction | 1.511 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Enantioselective actions of 4-amino-3-hydroxybutanoic acid and (3-amino-2-hydroxypropyl)methylphosphinic acid at recombinant GABA(C) receptors.
Bioorg. Med. Chem. Lett. 18 , 402-4, (2008) The R- and S-enantiomers of 4-amino-3-hydroxybutanoic acid (GABOB) were full agonists at human recombinant rho1 GABA(C) receptors. Their enantioselectivity (R>S) matched that reported for their agonis... |
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GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.
J. Med. Chem. 28(11) , 1612-7, (1985) (RS)-5-(Aminomethyl)-2-isoxazolin-3-ol (dihydromuscimol, DHM) is a potent 4-aminobutyric acid (GABA) agonist, the inhibitory effects of which on neurons are sensitive to the antagonist bicuculline met... |
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Formation of gamma-amino-beta-hydroxybutyric acid from 2-hydroxyputrescine in rat brain.
J. Neurochem. 51(2) , 548-51, (1988) gamma-Amino-beta-[3H]hydroxybutyric acid ([3H]-GABOB) was formed in rat brain from 2-[3H]-hydroxyputrescine that had been chemically synthesized from 2-oxoputrescine and [3H]sodium borohydride. After ... |
3-Hydroxy-4-aminobutyric acid |
γ-amino-β-hydroxybutyric acid |
(S)-4-AMINO-3-HYDROXYBUTANOIC ACID |
3-hydroxy-4-amino-butyric acid (GABOB) |
3-hydroxy-GABA |
β-Hydroxy-GABA |
3-hydroxy-4-amino-butyric acid |
Butanoic acid, 4-amino-3-hydroxy- |
(S)-(+)-GABOB |
acide (S)-amino-4 hydroxy-3 butanoique |
β-Hydroxy-γ-aminobutyric acid |
4-Amino-3-hydroxybutanoic acid |
(S)-(+)-Amino-3-hydroxybutanoic acid |
g-Amino-b-hydroxybutyric Acid |
DL-4-Amino-3-hydroxybutanoic acid |
DL-4-Amino-3-hydroxybutyric acid |
(S)-(+)-4-Amino-3-hydroxybutyric acid |
MFCD00672884 |
(±)-4-Amino-3-hydroxybutyric acid |
γ-Amino-β-hydroxy-n-butyric acid |
UNII:1ZHM019FLD |