(S)-(+)-4-Amino-3-hydroxybutyric acid

Modify Date: 2024-01-14 20:40:59

(S)-(+)-4-Amino-3-hydroxybutyric acid Structure
(S)-(+)-4-Amino-3-hydroxybutyric acid structure
Common Name (S)-(+)-4-Amino-3-hydroxybutyric acid
CAS Number 7013-05-0 Molecular Weight 119.119
Density 1.3±0.1 g/cm3 Boiling Point 374.5±32.0 °C at 760 mmHg
Molecular Formula C4H9NO3 Melting Point 207-212ºC
MSDS Chinese USA Flash Point 180.3±25.1 °C

 Use of (S)-(+)-4-Amino-3-hydroxybutyric acid


GABOB, also known as γ-Amino-β-hydroxybutyric acid, β-hydroxy-γ-aminobutyric acid, β-hydroxy-GABA, is an anticonvulsant which is used for the treatment of epilepsy in Europe, Japan, and Mexico. It is also an endogenous active metabolite and analogue of the neurotransmitter γ-aminobutyric acid (GABA), and for this reason, may function as a neurotransmitter itself.

 Names

Name (3S)-4-amino-3-hydroxybutanoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 374.5±32.0 °C at 760 mmHg
Melting Point 207-212ºC
Molecular Formula C4H9NO3
Molecular Weight 119.119
Flash Point 180.3±25.1 °C
Exact Mass 119.058243
PSA 83.55000
LogP -1.73
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.511

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

 Articles25

More Articles
Enantioselective actions of 4-amino-3-hydroxybutanoic acid and (3-amino-2-hydroxypropyl)methylphosphinic acid at recombinant GABA(C) receptors.

Bioorg. Med. Chem. Lett. 18 , 402-4, (2008)

The R- and S-enantiomers of 4-amino-3-hydroxybutanoic acid (GABOB) were full agonists at human recombinant rho1 GABA(C) receptors. Their enantioselectivity (R>S) matched that reported for their agonis...

GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.

J. Med. Chem. 28(11) , 1612-7, (1985)

(RS)-5-(Aminomethyl)-2-isoxazolin-3-ol (dihydromuscimol, DHM) is a potent 4-aminobutyric acid (GABA) agonist, the inhibitory effects of which on neurons are sensitive to the antagonist bicuculline met...

Formation of gamma-amino-beta-hydroxybutyric acid from 2-hydroxyputrescine in rat brain.

J. Neurochem. 51(2) , 548-51, (1988)

gamma-Amino-beta-[3H]hydroxybutyric acid ([3H]-GABOB) was formed in rat brain from 2-[3H]-hydroxyputrescine that had been chemically synthesized from 2-oxoputrescine and [3H]sodium borohydride. After ...

 Synonyms

3-Hydroxy-4-aminobutyric acid
γ-amino-β-hydroxybutyric acid
(S)-4-AMINO-3-HYDROXYBUTANOIC ACID
3-hydroxy-4-amino-butyric acid (GABOB)
3-hydroxy-GABA
β-Hydroxy-GABA
3-hydroxy-4-amino-butyric acid
Butanoic acid, 4-amino-3-hydroxy-
(S)-(+)-GABOB
acide (S)-amino-4 hydroxy-3 butanoique
β-Hydroxy-γ-aminobutyric acid
4-Amino-3-hydroxybutanoic acid
(S)-(+)-Amino-3-hydroxybutanoic acid
g-Amino-b-hydroxybutyric Acid
DL-4-Amino-3-hydroxybutanoic acid
DL-4-Amino-3-hydroxybutyric acid
(S)-(+)-4-Amino-3-hydroxybutyric acid
MFCD00672884
(±)-4-Amino-3-hydroxybutyric acid
γ-Amino-β-hydroxy-n-butyric acid
UNII:1ZHM019FLD
Top Suppliers:I want be here

  • DC Chemicals Limited
  • China
  • Product Name: GABOB
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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