Polyoxyl 15 hydroxystearate
Polyoxyl 15 hydroxystearate structure
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Common Name | Polyoxyl 15 hydroxystearate | ||
|---|---|---|---|---|
| CAS Number | 70142-34-6 | Molecular Weight | 963.23800 | |
| Density | 1.048 g/cm3 at 20 °C | Boiling Point | N/A | |
| Molecular Formula | C47H94O19 | Melting Point | 25-30 °C | |
| MSDS | Chinese USA | Flash Point | 272 ℃ | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Polyoxyl 15 hydroxystearatePolyoxyl 15 hydroxystearate is a nonionic surfactant and emulsifier. Polyoxyl 15 hydroxystearate is used for improving the solubility and dissolution of poorly watersoluble drugs[1][2]. |
| Name | 11-hydroxy-17-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]heptadecanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Polyoxyl 15 hydroxystearate is a nonionic surfactant and emulsifier. Polyoxyl 15 hydroxystearate is used for improving the solubility and dissolution of poorly watersoluble drugs[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Polyoxyl 15 hydroxystearate is found to be effective in enhancing the solubility and stability of Curcumin (HY-N0005)[2]. Polyoxyl 15 hydroxystearate is employed as a carrier to build up a stable CoQ10-loaded micelle delivery system[3]. |
| References |
| Density | 1.048 g/cm3 at 20 °C |
|---|---|
| Melting Point | 25-30 °C |
| Molecular Formula | C47H94O19 |
| Molecular Weight | 963.23800 |
| Flash Point | 272 ℃ |
| Exact Mass | 962.63900 |
| PSA | 216.21000 |
| LogP | 4.13460 |
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Detrimental role of the EP1 prostanoid receptor in blood-brain barrier damage following experimental ischemic stroke.
Sci. Rep. 5 , 17956, (2015) Cyclooxygenase-2 (COX-2) is activated in response to ischemia and significantly contributes to the neuroinflammatory process. Accumulation of COX-2-derived prostaglandin E2 (PGE2) parallels the substa... |
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Solutol HS 15, nontoxic polyoxyethylene esters of 12-hydroxystearic acid, reverses multidrug resistance.
Cancer Res. 51 , 897-902, (1991) A recently developed non-ionic surfactant called Solutol HS 15 (poly-oxyethylene esters of 12-hydroxystearic acid), with low toxicity in vivo, was shown to reverse completely the multidrug resistance ... |
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Novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of lipophilic cyclosporine A: in vitro and in vivo results.
Int. J. Pharm. 365(1-2) , 143-149, (2009) The objective of the present study was to design a novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of a lipophilic drug, cyclosporine A (CsA). A CsA-loaded mic... |
| Polyethylene glycol (15)-hydroxystearate |
| Polyoxyethylated 12-hydroxystearic acid |
| Macrogol (15)-hydroxystearate |