2-(2-METHYL-4-NITRO-IMIDAZOL-1-YL)-ETHANOL

Modify Date: 2025-09-01 12:25:56

2-(2-METHYL-4-NITRO-IMIDAZOL-1-YL)-ETHANOL Structure
2-(2-METHYL-4-NITRO-IMIDAZOL-1-YL)-ETHANOL structure
Common Name 2-(2-METHYL-4-NITRO-IMIDAZOL-1-YL)-ETHANOL
CAS Number 705-19-1 Molecular Weight 171.15400
Density 1.45 g/cm3 Boiling Point 405.4ºC at 760 mmHg
Molecular Formula C6H9N3O3 Melting Point N/A
MSDS N/A Flash Point 199ºC

 Use of 2-(2-METHYL-4-NITRO-IMIDAZOL-1-YL)-ETHANOL


Isometronidazole is a hypoxic cell sensitizer. Isometronidazole (750 mg/kg) shows an efficacy as a hypoxic cell sensitizer in severely hypoxic FaDu tumors but not in less hypoxic GL tumors.

 Names

Name 2-(2-methyl-4-nitroimidazol-1-yl)ethanol
Synonym More Synonyms

  Biological Activity

Description Isometronidazole is a hypoxic cell sensitizer. Isometronidazole (750 mg/kg) shows an efficacy as a hypoxic cell sensitizer in severely hypoxic FaDu tumors but not in less hypoxic GL tumors.
Related Catalog
References

[1]. Schreiber A, et al. Effect of the hypoxic cell sensitizer isometronidazole on local control of two human squamous cell carcinomas after fractionated irradiation. Strahlenther Onkol. 2004;180(6):375-382.  

 Chemical & Physical Properties

Density 1.45 g/cm3
Boiling Point 405.4ºC at 760 mmHg
Molecular Formula C6H9N3O3
Molecular Weight 171.15400
Flash Point 199ºC
Exact Mass 171.06400
PSA 83.87000
LogP 0.61520
Index of Refraction 1.612

 Synonyms

R.P. 8979
Izoklion
1H-Imidazole-1-ethanol,2-methyl-4-nitro
2-methyl-4-nitroimidazole-1-ethanol
2-Methyl-4-nitro-1H-imidazole-1-ethanol
Isometronidazole
1-(2-hydroxyethyl)-2-methyl-4-nitro-1H-imidazole
2-(2-Methyl-4-nitro-imidazol-1-yl)-ethanol
2-(2-methyl-4-nitro-1H-imidazol-1-yl)ethanol
Imidazole-1-ethanol,2-methyl-4-nitro
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