705-19-1

705-19-1 structure

Name: 2-(2-METHYL-4-NITRO-IMIDAZOL-1-YL)-ETHANOL
Chemical Name: 2-(2-methyl-4-nitroimidazol-1-yl)ethanol
CAS Number: 705-19-1
Molecular Formula: C₆H₉N₃O₃
Molecular Weight: 171.15400
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-08-29 06:54:37
Modify Date: 2025-09-01 12:25:56
Isometronidazole is a hypoxic cell sensitizer. Isometronidazole (750 mg/kg) shows an efficacy as a hypoxic cell sensitizer in severely hypoxic FaDu tumors but not in less hypoxic GL tumors.

Name	2-(2-methyl-4-nitroimidazol-1-yl)ethanol
Synonyms	R.P. 8979 Izoklion 1H-Imidazole-1-ethanol,2-methyl-4-nitro 2-methyl-4-nitroimidazole-1-ethanol 2-Methyl-4-nitro-1H-imidazole-1-ethanol Isometronidazole 1-(2-hydroxyethyl)-2-methyl-4-nitro-1H-imidazole 2-(2-Methyl-4-nitro-imidazol-1-yl)-ethanol 2-(2-methyl-4-nitro-1H-imidazol-1-yl)ethanol Imidazole-1-ethanol,2-methyl-4-nitro

Description	Isometronidazole is a hypoxic cell sensitizer. Isometronidazole (750 mg/kg) shows an efficacy as a hypoxic cell sensitizer in severely hypoxic FaDu tumors but not in less hypoxic GL tumors.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Schreiber A, et al. Effect of the hypoxic cell sensitizer isometronidazole on local control of two human squamous cell carcinomas after fractionated irradiation. Strahlenther Onkol. 2004;180(6):375-382.

696-23-1

540-51-2

~22%

705-19-1

696-23-1

107-07-3

~93%

705-19-1

Literature: Liu; Chen; Cao; Li Synthetic Communications, 1993 , vol. 23, # 18 p. 2611 - 2615