ETHYL 4-HYDROXY-2-PHENYL-1,3-THIAZOLE-5-CARBOXYLATE
ETHYL 4-HYDROXY-2-PHENYL-1,3-THIAZOLE-5-CARBOXYLATE structure
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Common Name | ETHYL 4-HYDROXY-2-PHENYL-1,3-THIAZOLE-5-CARBOXYLATE | ||
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| CAS Number | 70547-29-4 | Molecular Weight | 249.28600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H11NO3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Summary: The chemical is 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one (Chinese name: 4-羟基-2-苯基-1,3-噻唑-5-羧酸乙酯) with CAS number 70547-29-4, molecular formula C12H11NO3S, and molecular weight 249.28600. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C12H11NO3S |
|---|---|
| Molecular Weight | 249.28600 |
| Exact Mass | 249.04600 |
| PSA | 87.66000 |
| LogP | 2.69240 |
| InChIKey | QKRYFBKKMLYRHO-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1sc(-c2ccccc2)nc1O |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2934100090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~87%
ETHYL 4-HYDROXY... CAS#:70547-29-4 |
| Literature: TAKEDA PHARMACEUTICAL COMPANY LIMITED Patent: WO2007/89031 A1, 2007 ; Location in patent: Page/Page column 88 ; WO 2007/089031 A1 |
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~93%
ETHYL 4-HYDROXY... CAS#:70547-29-4 |
| Literature: Yavari, Issa; Sayyed-Alangi, S. Zahra; Hajinasiri, Rahimeh; Sajjadi-Ghotbabadi, Hadi Monatshefte fur Chemie, 2009 , vol. 140, # 2 p. 209 - 211 |
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~60%
ETHYL 4-HYDROXY... CAS#:70547-29-4 |
| Literature: Dridi, Khaireddine; El Efrit, Mohamed Lotfi; Zantour, Hedi Phosphorus, Sulfur and Silicon and Related Elements, 1998 , vol. 134-135, p. 407 - 412 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
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| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934100090 |
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| Summary | 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: The compound was tested for the in vitro inhibition of 5-lipoxygenase (5-lo) from the...
Source: ChEMBL
Target: Polyunsaturated fatty acid 5-lipoxygenase
External Id: CHEMBL618261
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Name: Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in ethyl 4-...
Source: ChEMBL
Target: Transient receptor potential cation channel subfamily M member 8
External Id: CHEMBL5265491
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Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
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Name: Inhibition of CDK2/Cyclin-E (unknown origin) using maltose binding protein as substra...
Source: ChEMBL
Target: G1/S-specific cyclin-E1
External Id: CHEMBL3266078
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Name: Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-...
Source: ChEMBL
Target: Protein DBF4 homolog A
External Id: CHEMBL3266077
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Ethyl 4-hydroxy-2-phenyl-1,3-thiazole-5-carboxylate |
| 2-phenyl-4-hydroxy-5-carbethoxythiazole |
| 4-oxo-2-phenyl-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester |
| ethyl 4-hydroxy-2-phenylthiazole-5-carboxylate |
| 4-hydroxy-2-phenyl-thiazole-5-carboxylic acid ethyl ester |
| 2-Phenyl-4-hydroxy-5-(methylcarbomethoxy)-thiazole |
| 2-Phenyl-4-ethoxycarbonyl-5-hydroxythiazol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the upstream materials of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one? |
| A: Related upstream materials(CAS) of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one: 685-87-0;2227-79-4;14064-10-9;33243-90-2;623-51-8. |
| Q: What is the English name of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one? |
| A: The English name of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one is 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one. |
| Q: What is the InChIKey of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one? |
| A: InChIKey of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one is QKRYFBKKMLYRHO-UHFFFAOYSA-N. |
| Q: What is the LogP of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one? |
| A: LogP of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one is 2.69240. |
| Q: What English synonyms does 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one have? |
| A: English synonyms of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one: Ethyl 4-hydroxy-2-phenyl-1,3-thiazole-5-carboxylate, 2-phenyl-4-hydroxy-5-carbethoxythiazole, 4-oxo-2-phenyl-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester, ethyl 4-hydroxy-2-phenylthiazole-5-carboxylate, 4-hydroxy-2-phenyl-thiazole-5-carboxylic acid ethyl ester, 2-Phenyl-4-hydroxy-5-(methylcarbomethoxy)-thiazole, 2-Phenyl-4-ethoxycarbonyl-5-hydroxythiazol. |
| Q: What is the polar surface area (PSA) of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one? |
| A: Polar surface area (PSA) of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one is 87.66000. |
| Q: What is the molecular weight of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one? |
| A: Molecular weight of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one is 249.28600. |
| Q: What is the CAS number of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one? |
| A: CAS number of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one is 70547-29-4. |
| Q: What is the SMILES notation of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one? |
| A: SMILES notation of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one is CCOC(=O)c1sc(-c2ccccc2)nc1O. |
| Q: What is the molecular formula of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one? |
| A: Molecular formula of 5-[ethoxy(hydroxy)methylidene]-2-phenyl-1,3-thiazol-4-one is C12H11NO3S. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |