ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate

Modify Date: 2024-01-09 20:15:22

ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate Structure
ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate structure
Common Name ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate
CAS Number 7064-35-9 Molecular Weight 159.18500
Density 1.36g/cm3 Boiling Point 495.1ºC at 760 mmHg
Molecular Formula C10H9NO Melting Point N/A
MSDS N/A Flash Point 253.2ºC

 Names

Name 5-(4-methylphenyl)-1,2-oxazole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.36g/cm3
Boiling Point 495.1ºC at 760 mmHg
Molecular Formula C10H9NO
Molecular Weight 159.18500
Flash Point 253.2ºC
Exact Mass 159.06800
PSA 26.03000
LogP 2.65000
Index of Refraction 1.645

 Safety Information

Hazard Codes Xi
HS Code 2934999090

 Synthetic Route

~89%

ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate Structure

ethyl 1-[5-cyan...

CAS#:7064-35-9

Literature: Kivrak, Arif; Zora, Metin Tetrahedron, 2014 , vol. 70, # 4 p. 817 - 831

~%

ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate Structure

ethyl 1-[5-cyan...

CAS#:7064-35-9

Literature: Novartis AG Patent: US5977075 A1, 1999 ; US 5977075 A

~%

ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate Structure

ethyl 1-[5-cyan...

CAS#:7064-35-9

Literature: Swain, Christopher J.; Teran, Ana; Maroto, Marta; Cabello, Angeles Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6058 - 6062

~%

ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate Structure

ethyl 1-[5-cyan...

CAS#:7064-35-9

Literature: Swain, Christopher J.; Teran, Ana; Maroto, Marta; Cabello, Angeles Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 23 p. 6058 - 6062

~%

ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate Structure

ethyl 1-[5-cyan...

CAS#:7064-35-9

Literature: Molina, P.; Fresneda, P. M. Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 461 - 464

~%

ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate Structure

ethyl 1-[5-cyan...

CAS#:7064-35-9

Literature: Sakaki, Junichi; Murata, Toshiki; Yuumoto, Yoko; Nakamura, Ikushi; Frueh, Thomas; Pitterna, Thomas; Iwasaki, Genji; Oda, Kyoko; Yamamura, Takaki; Hayakawa, Kenji Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 16 p. 2241 - 2246

~%

ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate Structure

ethyl 1-[5-cyan...

CAS#:7064-35-9

Literature: Kotschetkow et al. Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 452,456; engl. Ausg. S. 511, 514

~%

ethyl 1-[5-cyano-4-methyl-3-[(3-methyl-4-oxo-2-sulfanylidene-thiazolidin-5-ylidene)methyl]-6-oxo-1-propyl-pyridin-2-yl]piperidine-3-carboxylate Structure

ethyl 1-[5-cyan...

CAS#:7064-35-9

Literature: Woodward,R.B. et al. Tetrahedron, Supplement, 1966 , vol. 8, p. 321 - 340

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

5-(p-tolyl)-isoxazole
5-(4-methyl-phenyl)-isoxazole
4-(Isoxazol-5-yl)toluene
5-p-Tolyl-isoxazol
4-(5-isoxazolyl)toluene