3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione

Modify Date: 2024-01-23 21:19:20

3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione Structure
3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione structure
Common Name 3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione
CAS Number 707-09-5 Molecular Weight 182.22000
Density 1.22g/cm3 Boiling Point N/A
Molecular Formula C9H14N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.22g/cm3
Molecular Formula C9H14N2O2
Molecular Weight 182.22000
Exact Mass 182.10600
PSA 49.41000
LogP 1.13760
Index of Refraction 1.548

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HM2770000
CHEMICAL NAME :
1,3-Diazaspiro(4.5)decane-2,4-dione, 3-methyl-
CAS REGISTRY NUMBER :
707-09-5
BEILSTEIN REFERENCE NO. :
0157527
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C9-H14-N2-O2
MOLECULAR WEIGHT :
182.25
WISWESSER LINE NOTATION :
T5MVNVXJ C1 E-& AL6XTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1100 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - stiffness
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,239,1965

 Synthetic Route

~74%

3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione Structure

3-methyl-1,3-di...

CAS#:707-09-5

Literature: Pedregal; Trigo; Espada; et al. Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 2 p. 477 - 480

~%

3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione Structure

3-methyl-1,3-di...

CAS#:707-09-5

Literature: Lilly Industries Limited Patent: US4230709 A1, 1980 ;

~%

3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione Structure

3-methyl-1,3-di...

CAS#:707-09-5

Literature: Courtoison; Coudert; Couquelet; Tronche; Jonadet; Bastide Farmaco, Edizione Scientifica, 1988 , vol. 43, # 2 p. 153 - 160

~34%

3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione Structure

3-methyl-1,3-di...

CAS#:707-09-5

Literature: Courtoison; Coudert; Couquelet; Tronche; Jonadet; Bastide Farmaco, Edizione Scientifica, 1988 , vol. 43, # 2 p. 153 - 160

~%

3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione Structure

3-methyl-1,3-di...

CAS#:707-09-5

Literature: Salazar, Loreto; Rubido, Julia; Espada, Modesta; Pedregal, Carmen; Trigo, Gregorio; Elguero, Jose Journal of Heterocyclic Chemistry, 1986 , vol. 23, p. 481 - 485

~%

3-methyl-1,3-diazaspiro[4.5]decane-2,4-dione Structure

3-methyl-1,3-di...

CAS#:707-09-5

Literature: Carrington; Waring Journal of the Chemical Society, 1950 , p. 354,366

 Synonyms

3'-Methyl-cyclohexanspiro-5'-hydantoin
3'-Methylcyclohexanespiro-5'-hydantoin
3-Methyl-5,5-pentamethylen-hydantoin
1,4-dione,3-methyl