2-Deoxy-2-fluoro-L-fucose
Modify Date: 2024-01-21 11:08:21
2-Deoxy-2-fluoro-L-fucose structure
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Common Name | 2-Deoxy-2-fluoro-L-fucose | ||
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| CAS Number | 70763-62-1 | Molecular Weight | 166.14800 | |
| Density | 1.335g/cm3 | Boiling Point | 386.5ºC at 760 mmHg | |
| Molecular Formula | C6H11FO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 187.6ºC | |
Use of 2-Deoxy-2-fluoro-L-fucose2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma[1]. |
| Name | 2-Deoxy-2-fluoro-L-fucose |
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| Description | 2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma[1]. |
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| Related Catalog | |
| In Vitro | 2-Deoxy-2-fluoro-L-fucose (2FF) (100-500 μM)) suppresses fucosylation in 4T1 cells[1]. 2-Deoxy-2-fluoro-L-fucose (100 μM; 4T1 cells) decreases phosphorylation of Smad 1/5 and Smad 2[1]. |
| References |
| Density | 1.335g/cm3 |
|---|---|
| Boiling Point | 386.5ºC at 760 mmHg |
| Molecular Formula | C6H11FO4 |
| Molecular Weight | 166.14800 |
| Flash Point | 187.6ºC |
| Exact Mass | 166.06400 |
| PSA | 69.92000 |
| Index of Refraction | 1.469 |
| Hazard Codes | Xi |
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