1-Methyluric acid

Modify Date: 2024-01-10 18:53:52

1-Methyluric acid Structure
1-Methyluric acid structure
Common Name 1-Methyluric acid
CAS Number 708-79-2 Molecular Weight 182.13700
Density 1.73g/cm3 Boiling Point 315.51°C (rough estimate)
Molecular Formula C6H6N4O3 Melting Point >325ºC
MSDS Chinese USA Flash Point N/A

 Use of 1-Methyluric acid


1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels.

 Names

Name 1-methyluric acid
Synonym More Synonyms

 1-Methyluric acid Biological Activity

Description 1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels.
Related Catalog
Target

Human Endogenous Metabolite

In Vivo Perfusion of the urinary bladder with 1-Methyl uric acid solution shows an increase in the serum total cholesterol level, true triglyceride level, glucose level and insulin level on comparison with perfusion of the urinary bladder with distilled water[1].
Animal Admin Rats[1] Adult albino rats of Wistar strain of either sex weighing 200-300 g rats are used for the present study. Thirty albino rats are divided into three groups of ten each. Group I serves as the control group perfused with distilled water. Following cannulation, the bladder is perfused with distilled water. Group II serves as the uric acid perfused group. Group III serves as the 1-Methyl uric acid perfused group. The animals of this group are treated in a similar way as those of control group (Group I) except that the bladder is perfused with the aqueous solution of 1-Methyl uric acid (0.0024 g/100 mL) instead of distilled water[1].
References

[1]. Balasubramanian T, et al. Uric acid or 1-methyl uric acid in the urinary bladder increases serum glucose, insulin, true triglyceride, and total cholesterol levels in Wistar rats. ScientificWorldJournal. 2003 Oct 5;3:930-6.

 Chemical & Physical Properties

Density 1.73g/cm3
Boiling Point 315.51°C (rough estimate)
Melting Point >325ºC
Molecular Formula C6H6N4O3
Molecular Weight 182.13700
Exact Mass 182.04400
PSA 103.51000
Index of Refraction 1.695
Storage condition Refrigerator

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

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1-Methyluric acid Structure

1-Methyluric acid

CAS#:708-79-2

Literature: Journal of Heterocyclic Chemistry, , vol. 24, p. 1109 - 1116

~%

1-Methyluric acid Structure

1-Methyluric acid

CAS#:708-79-2

Literature: Justus Liebigs Annalen der Chemie, , vol. 441, p. 209

~%

1-Methyluric acid Structure

1-Methyluric acid

CAS#:708-79-2

Literature: Biological and Pharmaceutical Bulletin, , vol. 18, # 1 p. 75 - 81

~%

1-Methyluric acid Structure

1-Methyluric acid

CAS#:708-79-2

Literature: Justus Liebigs Annalen der Chemie, , vol. 413, p. 133

~%

1-Methyluric acid Structure

1-Methyluric acid

CAS#:708-79-2

Literature: Justus Liebigs Annalen der Chemie, , vol. 413, p. 133

~%

1-Methyluric acid Structure

1-Methyluric acid

CAS#:708-79-2

Literature: Justus Liebigs Annalen der Chemie, , vol. 515, p. 201,250

~%

1-Methyluric acid Structure

1-Methyluric acid

CAS#:708-79-2

Literature: Justus Liebigs Annalen der Chemie, , vol. 515, p. 201,250

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

1-methyl-8-oxyxanthine
1-Methyluric acid
1-Methylurate
1MUA
1-methyl-7,9-dihydro-3H-purine-2,6,8-trione
1-Methyl-2,6,8-trihydroxypurine
1-Methyl-harnsaeure