1-Methyluric acid
1-Methyluric acid structure
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Common Name | 1-Methyluric acid | ||
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| CAS Number | 708-79-2 | Molecular Weight | 182.13700 | |
| Density | 1.73g/cm3 | Boiling Point | 315.51°C (rough estimate) | |
| Molecular Formula | C6H6N4O3 | Melting Point | >325ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of 1-Methyluric acid1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels. |
Summary: 1-U 1-甲基-2,6,8-三羟基嘌呤 (1MUA)，also known as 1-methyluric acid, has a CAS number of 708-79-2, with a molecular formula of C6H6N4O3 and a molecular weight of 182.14. Its melting point is greater than 325°C. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 1-methyluric acid |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vivo | Perfusion of the urinary bladder with 1-Methyl uric acid solution shows an increase in the serum total cholesterol level, true triglyceride level, glucose level and insulin level on comparison with perfusion of the urinary bladder with distilled water[1]. |
| Animal Admin | Rats[1] Adult albino rats of Wistar strain of either sex weighing 200-300 g rats are used for the present study. Thirty albino rats are divided into three groups of ten each. Group I serves as the control group perfused with distilled water. Following cannulation, the bladder is perfused with distilled water. Group II serves as the uric acid perfused group. Group III serves as the 1-Methyl uric acid perfused group. The animals of this group are treated in a similar way as those of control group (Group I) except that the bladder is perfused with the aqueous solution of 1-Methyl uric acid (0.0024 g/100 mL) instead of distilled water[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.73g/cm3 |
|---|---|
| Boiling Point | 315.51°C (rough estimate) |
| Melting Point | >325ºC |
| Molecular Formula | C6H6N4O3 |
| Molecular Weight | 182.13700 |
| Exact Mass | 182.04400 |
| PSA | 103.51000 |
| Index of Refraction | 1.695 |
| InChIKey | QFDRTQONISXGJA-UHFFFAOYSA-N |
| SMILES | Cn1c(=O)[nH]c2[nH]c(=O)[nH]c2c1=O |
| Storage condition | Refrigerator |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933990090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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1-Methyluric acid CAS#:708-79-2 |
| Literature: Journal of Heterocyclic Chemistry, , vol. 24, p. 1109 - 1116 |
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1-Methyluric acid CAS#:708-79-2 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 441, p. 209 |
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1-Methyluric acid CAS#:708-79-2 |
| Literature: Biological and Pharmaceutical Bulletin, , vol. 18, # 1 p. 75 - 81 |
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1-Methyluric acid CAS#:708-79-2 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 413, p. 133 |
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1-Methyluric acid CAS#:708-79-2 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 413, p. 133 |
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1-Methyluric acid CAS#:708-79-2 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 515, p. 201,250 |
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1-Methyluric acid CAS#:708-79-2 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 515, p. 201,250 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 7 | |
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| DownStream 2 | |
CAS#:569-34-6This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Altered age-related changes in bioenergetic properties and mitochondrial morphology in fibroblasts from sporadic amyotrophic lateral sclerosis patients.
Neurobiol. Aging 36 , 2893-903, (2015) Mitochondria play a key role in aging, which is a well-established risk factor in amyotrophic lateral sclerosis (ALS). We have previously modeled metabolic dysregulation in ALS using fibroblasts isola... |
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Pyogranulomatous pneumonia in goats caused by an undescribed Porphyromonas species, "Porphyromonas katsikii".
J. Clin. Microbiol. 53(3) , 795-8, (2015) A yet-undescribed bacterial species, tentatively named "Porphyromonas katsikii," was isolated from individuals of a small goat herd with pyogranulomatous pneumonia during an outbreak of acute respirat... |
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Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?
Eur. J. Clin. Pharmacol. 65(4) , 411-7, (2009) Individual activities of N-acetyltransferase 2 (NAT2) and of xanthine oxidase (XO) can be assessed using ratios of urinary caffeine metabolites. We investigated how ratios changed over time and which ... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 1-methyl-8-oxyxanthine |
| 1-Methyluric acid |
| 1-Methylurate |
| 1MUA |
| 1-methyl-7,9-dihydro-3H-purine-2,6,8-trione |
| 1-Methyl-2,6,8-trihydroxypurine |
| 1-Methyl-harnsaeure |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the CAS number of 1-methyluric acid? |
| A: CAS number of 1-methyluric acid is 708-79-2. |
| Q: What is the boiling point of 1-methyluric acid? |
| A: Boiling point of 1-methyluric acid is 315.51°C (rough estimate). |
| Q: What is the SMILES notation of 1-methyluric acid? |
| A: SMILES notation of 1-methyluric acid is Cn1c(=O)[nH]c2[nH]c(=O)[nH]c2c1=O. |
| Q: What is the polar surface area (PSA) of 1-methyluric acid? |
| A: Polar surface area (PSA) of 1-methyluric acid is 103.51000. |
| Q: What are the storage conditions for 1-methyluric acid? |
| A: Storage conditions for 1-methyluric acid: Refrigerator. |
| Q: What are the downstream products of 1-methyluric acid? |
| A: Related downstream products(CAS) of 1-methyluric acid: 944-73-0;569-34-6. |
| Q: What is the molecular weight of 1-methyluric acid? |
| A: Molecular weight of 1-methyluric acid is 182.13700. |
| Q: What are the uses of 1-methyluric acid? |
| A: Main uses of 1-methyluric acid: 1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels. |
| Q: What is the InChIKey of 1-methyluric acid? |
| A: InChIKey of 1-methyluric acid is QFDRTQONISXGJA-UHFFFAOYSA-N. |
| Q: What English synonyms does 1-methyluric acid have? |
| A: English synonyms of 1-methyluric acid: 1-methyl-8-oxyxanthine, 1-Methyluric acid, 1-Methylurate, 1MUA, 1-methyl-7,9-dihydro-3H-purine-2,6,8-trione, 1-Methyl-2,6,8-trihydroxypurine, 1-Methyl-harnsaeure. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |