2-[(Ethylamino)methyl]-4-nitrophenol

Modify Date: 2024-02-25 17:33:36

2-[(Ethylamino)methyl]-4-nitrophenol Structure
2-[(Ethylamino)methyl]-4-nitrophenol structure
Common Name 2-[(Ethylamino)methyl]-4-nitrophenol
CAS Number 71130-60-4 Molecular Weight 196.20300
Density 1.242g/cm3 Boiling Point 358.7ºC at 760 mmHg
Molecular Formula C9H12N2O3 Melting Point 200-201ºC
MSDS N/A Flash Point 170.8ºC

 Names

Name 2-(ethylaminomethyl)-4-nitrophenol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.242g/cm3
Boiling Point 358.7ºC at 760 mmHg
Melting Point 200-201ºC
Molecular Formula C9H12N2O3
Molecular Weight 196.20300
Flash Point 170.8ºC
Exact Mass 196.08500
PSA 78.08000
LogP 2.32400
Index of Refraction 1.579

 MSDS

Name: 2-((n-ethylamino)methyl)-4-nitrophenol Material Safety Data Sheet
Synonym:
CAS: 71130-60-4
Section 1 - Chemical Product MSDS Name:2-((n-ethylamino)methyl)-4-nitrophenol Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
71130-60-4 Phenol, 2-(ethylamino)methyl-4-nitro- unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
The toxicological properties of this material have not been investigated. Use appropriate procedures to prevent opportunities for direct contact with the skin or eyes and to prevent inhalation.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage:
Store in a cool, dry place. Keep container closed when not in use.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 71130-60-4: Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 0 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C9H12N2O3
Molecular Weight: 196.21

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, strong oxidants.
Incompatibilities with Other Materials:
Not available.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases.
Hazardous Polymerization: Not available.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 71130-60-4: SL4127500 LD50/LC50:
CAS# 71130-60-4: Oral, rat: LD50 = 1014 mg/kg.
Carcinogenicity:
Phenol, 2-(ethylamino)methyl-4-nitro- - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 71130-60-4: No information available.
Canada
CAS# 71130-60-4 is listed on Canada's NDSL List.
CAS# 71130-60-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 71130-60-4 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL4127500
CHEMICAL NAME :
Phenol, 2-((ethylamino)methyl)-4-nitro-
CAS REGISTRY NUMBER :
71130-60-4
LAST UPDATED :
199712
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H12-N2-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1014 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0522374
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0522374

 Synthetic Route

~70%

2-[(Ethylamino)methyl]-4-nitrophenol Structure

2-[(Ethylamino)...

CAS#:71130-60-4

Literature: Mei-lin Go; Tong-lan Ngiam; Wan Journal of Medicinal Chemistry, 1981 , vol. 24, # 12 p. 1471 - 1475

~%

2-[(Ethylamino)methyl]-4-nitrophenol Structure

2-[(Ethylamino)...

CAS#:71130-60-4

Literature: Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1467 - 1469

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

2-((Ethylamino)methyl)-4-nitrophenol
Phenol,2-((ethylamino)methyl)-4-nitro
N-Ethyl-2-hydroxy-5-nitrobenzenemethanamine
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