(RS)-1-(3-FLUOROPHENYL)ETHYLAMINE

Modify Date: 2024-01-07 20:03:28

(RS)-1-(3-FLUOROPHENYL)ETHYLAMINE Structure
(RS)-1-(3-FLUOROPHENYL)ETHYLAMINE structure
Common Name (RS)-1-(3-FLUOROPHENYL)ETHYLAMINE
CAS Number 71366-32-0 Molecular Weight 251.03500
Density 1.95g/cm3 Boiling Point 443.3ºC at 760 mmHg
Molecular Formula C6H7BrN2O4 Melting Point N/A
MSDS Chinese USA Flash Point 221.9ºC
Symbol GHS06
GHS06
Signal Word Danger

 Names

Name (rs)-4-bromo-homo-ibotenic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.95g/cm3
Boiling Point 443.3ºC at 760 mmHg
Molecular Formula C6H7BrN2O4
Molecular Weight 251.03500
Flash Point 221.9ºC
Exact Mass 249.95900
PSA 109.32000
LogP 0.38510
Index of Refraction 1.621

 MSDS

Name: (RS)-4-Bromo-homo-ibotenic acid Material Safety Data Sheet
Synonym: Br-HIBO; (RS)-a-Amino-4-bromo-3-hydroxy-5-isoazolepropionic aci
CAS: 71366-32-0
Section 1 - Chemical Product MSDS Name:(RS)-4-Bromo-homo-ibotenic acid Material Safety Data Sheet
Synonym:Br-HIBO; (RS)-a-Amino-4-bromo-3-hydroxy-5-isoazolepropionic aci

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
71366-32-0 (RS)-4-Bromo-homo-ibotenic acid unlisted
Hazard Symbols: T
Risk Phrases: 23/24/25

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed.Light sensitive.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Toxic in contact with skin.
Ingestion:
May cause irritation of the digestive tract. Poison by ingestion.
Inhalation:
May cause respiratory tract irritation. Toxic if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid immediately. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Keep refrigerated. (Store below 4C/39F.)

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 71366-32-0: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: white
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C6H7N2O4Br
Molecular Weight: 250.964

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials, light.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 71366-32-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
(RS)-4-Bromo-homo-ibotenic acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 38 In case of insufficient ventilation, wear
suitable respiratory equipment.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 71366-32-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 71366-32-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 71366-32-0 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301 + H311 + H331
Precautionary Statements P261-P280-P301 + P310-P311
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Risk Phrases 23/24/25
Safety Phrases 36/37/39-45
RIDADR UN 2811 6.1 / PGIII

 Articles10

More Articles
Turning behaviour and catalepsy after injection of excitatory amino acids into rat substantia nigra.

Neurosci. Lett. 23 , 337, (1981)

Unilateral injection of AMPA ((R,S)-alpha-3-hydroxyl-5-methyl-4-isoxazolepropionic acid), 4-bromohomoibotenic acid, kainic acid and N-methylaspartic acid into the caudal part of substantia nigra induc...

Excitatory amino acid agonists. Enzymic resolution, X-ray structure, and enantioselective activities of (R)- and (S)-bromohomoibotenic acid.

J. Med. Chem. 32(10) , 2254-60, (1989)

The enantiomers of alpha-amino-4-bromo-3-hydroxy-5-isoxazolepropionic acid (4-bromohomoibotenic acid, Br-HIBO, 1) a selective and potent agonist at one class of the central (S)-glutamic acid receptors...

Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2.

Proc. Natl. Acad. Sci. U. S. A. 102(34) , 12053-8, (2005)

Glutamate receptors (GluRs) are the most abundant mediators of the fast excitatory neurotransmission in the human brain. Agonists will, after activation of the receptors, induce different degrees of d...

 Synonyms

MFCD00153776
(+/-)-4-BROMOHOMOIBOTENIC ACID
(+-)-4-BROMOHOMOIBOTENIC ACID POTENT AMP A AGONIST
(RS)-A-AMINO-4-BROMO-3-HYDROXY-5-ISOXAZOLEPROPIONIC ACID
(R,S)-4-Bromo-homo-ibotenic acid
BR-HIBO
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