Cordycepin 5′-triphosphate sodium salt
Cordycepin 5′-triphosphate sodium salt structure
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Common Name | Cordycepin 5′-triphosphate sodium salt | ||
|---|---|---|---|---|
| CAS Number | 71997-32-5 | Molecular Weight | 579.10900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H12N5Na4O12P3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
| Name | tetrasodium,[[[(2S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C10H12N5Na4O12P3 |
|---|---|
| Molecular Weight | 579.10900 |
| Exact Mass | 578.92900 |
| PSA | 299.65000 |
| LogP | 1.73420 |
| InChIKey | XAHUGMVDQATLJY-PHWMRHDISA-J |
| SMILES | Nc1ncnc2c1ncn2C1OC(COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])CC1O.[Na+].[Na+].[Na+].[Na+] |
| Storage condition | 20°C |
| Symbol |
GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H332-H335-H351 |
| Precautionary Statements | P261-P281-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xn |
| Risk Phrases | 20/22-36/37/38-40 |
| Safety Phrases | 22-26-36-45 |
| RIDADR | NONH for all modes of transport |
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Characterization of DNA substrate specificities of apurinic/apyrimidinic endonucleases from Mycobacterium tuberculosis.
DNA Repair (Amst.) 33 , 1-16, (2015) Apurinic/apyrimidinic (AP) endonucleases are key enzymes involved in the repair of abasic sites and DNA strand breaks. Pathogenic bacteria Mycobacterium tuberculosis contains two AP endonucleases: Mtb... |
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Injection of exogenous RNA in amphibian oocytes leads to RNA level fluctuations which are sensitive to cordycepin, an RNA chain elongation terminator.
C R Biol. 326 , 1135-1147, (2003) Using an in vivo heterologous system to study the stability of Xenopus laevis RNA injected into axolotl (Ambystoma mexicanum) fertilized eggs, we have previously observed unexpected fluctuations in RN... |
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RNA-directed agent, cordycepin, induces cell death in multiple myeloma cells.
Br. J. Haematol. 140 , 682-691, (2008) Multiple myeloma (MM) is an incurable plasma cell malignancy that is slow-growing, and thus traditional DNA-replication directed chemotherapeutics are ineffective. We hypothesized that those agents th... |
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Name: Inhibition of DENV RNA-dependent RNA polymerase at 10 uM
Source: ChEMBL
Target: N/A
External Id: CHEMBL4668923
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Name: Inhibition of HCV NS5B polymerase assessed as chain termination of RNA synthesis
Source: ChEMBL
Target: N/A
External Id: CHEMBL983730
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Name: Experimentally measured binding affinity data (Kd) for protein-ligand complexes deriv...
Source: Shanghai Institute of Organic Chemistry
Target: N/A
External Id: PDBbind-Kd for protein-ligand complexes
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Name: Inhibition of DENV2 N-terminal His6-tagged NS5 protein expressed in Escherichia coli ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4334075
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Name: Inhibition of ZIKV N-terminal His6-tagged NS5 protein expressed in Escherichia coli u...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4334074
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Name: Ratio of IC50 for HCV NS5B polymerase S282T mutant to IC50 for HCV NS5B polymerase by...
Source: ChEMBL
Target: N/A
External Id: CHEMBL985670
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| 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE SODIUM |
| Adenosine5'-(tetrahydrogen triphosphate),3'-deoxy-,trisodium salt (9CI) |