5-Amino-1H-imidazole-4-carboxamide hydrochloride
5-Amino-1H-imidazole-4-carboxamide hydrochloride structure
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Common Name | 5-Amino-1H-imidazole-4-carboxamide hydrochloride | ||
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| CAS Number | 72-40-2 | Molecular Weight | 162.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C4H7ClN4O | Melting Point | 250-252 °C (dec.)(lit.) | |
| MSDS | USA | Flash Point | 269.6ºC | |
Use of 5-Amino-1H-imidazole-4-carboxamide hydrochloride5-Amino-3H-imidazole-4-carboxamide hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Amino-5-imidazolecarboxamide hydrochloride |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 5-Amino-3H-imidazole-4-carboxamide hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
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| Related Catalog |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Melting Point | 250-252 °C (dec.)(lit.) |
|---|---|
| Molecular Formula | C4H7ClN4O |
| Molecular Weight | 162.58 |
| Flash Point | 269.6ºC |
| Exact Mass | 162.030838 |
| PSA | 98.78000 |
| LogP | 1.35820 |
| InChIKey | MXCUYSMIELHIQL-UHFFFAOYSA-N |
| SMILES | Cl.NC(=O)c1[nH]cnc1N |
| Water Solubility | SOLUBLE |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
| Risk Phrases | R20/21/22 |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | NI3911000 |
| HS Code | 2933290090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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5-Amino-1H-imid... CAS#:72-40-2
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| Literature: US2011/230658 A1, ; |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 1 | |
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| DownStream 10 | |
CAS#:111105-67-0
CAS#:85622-93-1
CAS#:5098-11-3
CAS#:21190-16-9
CAS#:118966-30-6
CAS#:21343-04-4
CAS#:91026-74-3
CAS#:59695-49-7![Carbamic acid,[5-(aminocarbonyl)-1H-imidazol-4-yl]-, ethyl ester (9CI) structure](https://image.chemsrc.com/caspic/273/59727-29-6.png)
CAS#:59727-29-6
CAS#:3815-69-8This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium.
J. Ethnopharmacol. 169 , 210-8, (2015) Astragaloside IV and cycloastragenol are present together in Astragalus membranaceus Moench (Fabaceae) and this study aims to simultaneously investigate their regulation of endothelial homeostasis in ... |
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Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1.
Pharmacol. Res. 89 , 19-28, (2014) Adipose and endothelial dysfunction is tightly associated with cardiovascular diseases in obesity and insulin resistance. Because perivascular adipose tissue (PVAT) surrounds vessels directly and infl... |
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Quercetin oppositely regulates insulin-mediated glucose disposal in skeletal muscle under normal and inflammatory conditions: The dual roles of AMPK activation.
Mol. Nutr. Food. Res. 60 , 551-65, (2016) Quercetin is a dietary flavonoid whose role in the regulation of the activity of insulin remains controversial. Our study aimed to investigate how quercetin and its major metabolite quercetin-3-glucur... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-Amino-5-imidazolecarboxamide hydrochloride |
| 4-amino-1H-imidazole-5-carboxamide,hydrochloride |
| 4-Amino-1H-imidazole-5-carboxamide hydrochloride (1:1) |
| 5-Amino-3H-imidazole-4-carboxylic acid amide HCl |
| 5-Amino-4-imidazolecarboxamide hydrochloride |
| MFCD00012704 |
| EINECS 200-778-3 |
| 1H-Imidazole-4-carboxamide, 5-amino-, hydrochloride (1:1) |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the safety information for 4-Amino-5-imidazolecarboxamide hydrochloride? |
| A: Safety information for 4-Amino-5-imidazolecarboxamide hydrochloride: S22-S24/25. |
| Q: What is the molecular formula of 4-Amino-5-imidazolecarboxamide hydrochloride? |
| A: Molecular formula of 4-Amino-5-imidazolecarboxamide hydrochloride is C4H7ClN4O. |
| Q: What English synonyms does 4-Amino-5-imidazolecarboxamide hydrochloride have? |
| A: English synonyms of 4-Amino-5-imidazolecarboxamide hydrochloride: 4-Amino-5-imidazolecarboxamide hydrochloride, 4-amino-1H-imidazole-5-carboxamide,hydrochloride, 4-Amino-1H-imidazole-5-carboxamide hydrochloride (1:1), 5-Amino-3H-imidazole-4-carboxylic acid amide HCl, 5-Amino-4-imidazolecarboxamide hydrochloride, MFCD00012704, EINECS 200-778-3, 1H-Imidazole-4-carboxamide, 5-amino-, hydrochloride (1:1). |
| Q: What is the SMILES notation of 4-Amino-5-imidazolecarboxamide hydrochloride? |
| A: SMILES notation of 4-Amino-5-imidazolecarboxamide hydrochloride is Cl.NC(=O)c1[nH]cnc1N. |
| Q: What are the downstream products of 4-Amino-5-imidazolecarboxamide hydrochloride? |
| A: Related downstream products(CAS) of 4-Amino-5-imidazolecarboxamide hydrochloride: 111105-67-0;85622-93-1;5098-11-3;21190-16-9;118966-30-6;21343-04-4;91026-74-3;59695-49-7;59727-29-6;3815-69-8. |
| Q: What is the CAS number of 4-Amino-5-imidazolecarboxamide hydrochloride? |
| A: CAS number of 4-Amino-5-imidazolecarboxamide hydrochloride is 72-40-2. |
| Q: What is the LogP of 4-Amino-5-imidazolecarboxamide hydrochloride? |
| A: LogP of 4-Amino-5-imidazolecarboxamide hydrochloride is 1.35820. |
| Q: What are the upstream materials of 4-Amino-5-imidazolecarboxamide hydrochloride? |
| A: Related upstream materials(CAS) of 4-Amino-5-imidazolecarboxamide hydrochloride: 360-97-4. |
| Q: What is the English name of 4-Amino-5-imidazolecarboxamide hydrochloride? |
| A: The English name of 4-Amino-5-imidazolecarboxamide hydrochloride is 4-Amino-5-imidazolecarboxamide hydrochloride. |
| Q: What is the polar surface area (PSA) of 4-Amino-5-imidazolecarboxamide hydrochloride? |
| A: Polar surface area (PSA) of 4-Amino-5-imidazolecarboxamide hydrochloride is 98.78000. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |