Metandienone

Modify Date: 2026-07-03 17:35:00

Metandienone Structure
Metandienone structure
Common Name Metandienone
CAS Number 72-63-9 Molecular Weight 300.435
Density 1.1±0.1 g/cm3 Boiling Point 436.5±45.0 °C at 760 mmHg
Molecular Formula C20H28O2 Melting Point 165-166 °C
MSDS USA Flash Point 186.2±21.3 °C
Symbol GHS02 GHS07 GHS08
GHS02, GHS07, GHS08
Signal Word Danger

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name Methandrostenolone
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.1±0.1 g/cm3
Boiling Point 436.5±45.0 °C at 760 mmHg
Melting Point 165-166 °C
Molecular Formula C20H28O2
Molecular Weight 300.435
Flash Point 186.2±21.3 °C
Exact Mass 300.208923
PSA 37.30000
LogP 4.04
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.572
InChIKey XWALNWXLMVGSFR-HLXURNFRSA-N
SMILES CC12C=CC(=O)C=C1CCC1C2CCC2(C)C1CCC2(C)O
Storage condition 2-8°C

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BV8000000
CHEMICAL NAME :
Androsta-1,4-dien-3-one, 17-beta-hydroxy-17-alpha-methyl-
CAS REGISTRY NUMBER :
72-63-9
LAST UPDATED :
199504
WISWESSER LINE NOTATION :
L E5 B666 OV AHTTT&J A1 E1 FQ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
425 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
561 mg/kg/7Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
13 mg/kg
SEX/DURATION :
male 60 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
200 mg/kg
SEX/DURATION :
female 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
200 mg/kg
SEX/DURATION :
male 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
7 mg/kg
SEX/DURATION :
female 14 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - other measures of fertility

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg/10D (Intermittent)
REFERENCE :
VPITAR Voprosy Pitaniya. Problems of Nutrition. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11- 1952- Volume(issue)/page/year: 38(4),63,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5642 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 157 (estimated) No. of Female Employees: 72 (estimated)

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS02 GHS07 GHS08
GHS02, GHS07, GHS08
Signal Word Danger
Hazard Statements H225-H315-H360FD
Supplemental HS May form explosive peroxides.
Precautionary Statements P201-P210-P280-P308 + P313-P370 + P378-P403 + P235
Hazard Codes F,T
Risk Phrases 60-61-11-19-38
Safety Phrases 53-45
RIDADR 3249
WGK Germany 3
RTECS BV8000000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2942000000

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~75%

Metandienone Structure

Metandienone

CAS#:72-63-9

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Literature: Chen, Kaixiong; Liu, Chang; Deng, Le; Xu, Guangyu Steroids, 2010 , vol. 75, # 7 p. 513 - 516

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  1

DownStream  2

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2942000000

 Articles28

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Gingival pain: an unusual side effect of ziprasidone.

BMJ Case Rep. 2013 , doi:10.1136/bcr-2012-007577, (2013)

The patient is a 52-year-old man with schizophrenia who developed severe, unremitting gingival pain after his ziprasidone dosage was increased from 80 to 120 mg. His physical examination and laborator...

Screening for anabolic steroids in urine of forensic cases using fully automated solid phase extraction and LC-MS-MS.

J. Anal. Toxicol. 38(9) , 637-44, (2014)

A screening method for 18 frequently measured exogenous anabolic steroids and the testosterone/epitestosterone (T/E) ratio in forensic cases has been developed and validated. The method involves a ful...

Mass spectrometric behavior of anabolic androgenic steroids using gas chromatography coupled to atmospheric pressure chemical ionization source. Part I: ionization.

J. Mass Spectrom. 49(6) , 509-21, (2014)

The detection of anabolic androgenic steroids (AAS) is one of the most important topics in doping control analysis. Gas chromatography coupled to (tandem) mass spectrometry (GC-MS(/MS)) with electron ...

 MetandienoneBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1-Dehydro-17a-methyltestosterone
1-Dehydro-17α-methyltestosterone
EINECS 200-787-2
(17β)-17-Hydroxy-17-methylandrosta-1,4-dien-3-one
17a-Methyl-17b-hydroxyandrosta-1,4-dien-3-one
17-β-hydroxy-17-methyl-androsta-1,4-dien-3-one (9CI)
Metandienone
(17b)-17-Hydroxy-17-methylandrosta-1,4-dien-3-one
Nabolin
17-β-hydroxy-17-methyl-androsta-1,4-dien-3-one
Methandienone
Methandrostenolone
MFCD00003650

 Metandienone | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the melting point of Methandrostenolone?
A: Melting point of Methandrostenolone is 165-166 °C.
Q: What is the English name of Methandrostenolone?
A: The English name of Methandrostenolone is Methandrostenolone.
Q: What is the molecular formula of Methandrostenolone?
A: Molecular formula of Methandrostenolone is C20H28O2.
Q: What is the boiling point of Methandrostenolone?
A: Boiling point of Methandrostenolone is 436.5±45.0 °C at 760 mmHg.
Q: What is the safety information for Methandrostenolone?
A: Safety information for Methandrostenolone: 53-45.
Q: What is the polar surface area (PSA) of Methandrostenolone?
A: Polar surface area (PSA) of Methandrostenolone is 37.30000.
Q: What English synonyms does Methandrostenolone have?
A: English synonyms of Methandrostenolone: 1-Dehydro-17a-methyltestosterone, 1-Dehydro-17α-methyltestosterone, EINECS 200-787-2, (17β)-17-Hydroxy-17-methylandrosta-1,4-dien-3-one, 17a-Methyl-17b-hydroxyandrosta-1,4-dien-3-one, 17-β-hydroxy-17-methyl-androsta-1,4-dien-3-one (9CI), Metandienone, (17b)-17-Hydroxy-17-methylandrosta-1,4-dien-3-one, Nabolin, 17-β-hydroxy-17-methyl-androsta-1,4-dien-3-one, Methandienone, Methandrostenolone, MFCD00003650.
Q: What is the molecular weight of Methandrostenolone?
A: Molecular weight of Methandrostenolone is 300.435.
Q: What is the InChIKey of Methandrostenolone?
A: InChIKey of Methandrostenolone is XWALNWXLMVGSFR-HLXURNFRSA-N.
Q: What is the SMILES notation of Methandrostenolone?
A: SMILES notation of Methandrostenolone is CC12C=CC(=O)C=C1CCC1C2CCC2(C)C1CCC2(C)O.

 Metandienonefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
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