Metandienone

Modify Date: 2024-01-02 17:20:43

Metandienone Structure
Metandienone structure
 Common Name Metandienone
CAS Number 72-63-9 Molecular Weight 300.435
Density 1.1±0.1 g/cm3 Boiling Point 436.5±45.0 °C at 760 mmHg
Molecular Formula C20H28O2 Melting Point 165-166 °C
MSDS USA Flash Point 186.2±21.3 °C
Symbol GHS02 GHS07 GHS08
GHS02, GHS07, GHS08		 Signal Word Danger

 Names

Name Methandrostenolone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 436.5±45.0 °C at 760 mmHg
Melting Point 165-166 °C
Molecular Formula C20H28O2
Molecular Weight 300.435
Flash Point 186.2±21.3 °C
Exact Mass 300.208923
PSA 37.30000
LogP 4.04
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.572
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BV8000000
CHEMICAL NAME :
Androsta-1,4-dien-3-one, 17-beta-hydroxy-17-alpha-methyl-
CAS REGISTRY NUMBER :
72-63-9
LAST UPDATED :
199504
WISWESSER LINE NOTATION :
L E5 B666 OV AHTTT&J A1 E1 FQ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
425 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
561 mg/kg/7Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
13 mg/kg
SEX/DURATION :
male 60 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
200 mg/kg
SEX/DURATION :
female 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
200 mg/kg
SEX/DURATION :
male 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
7 mg/kg
SEX/DURATION :
female 14 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Fertility - other measures of fertility

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg/10D (Intermittent)
REFERENCE :
VPITAR Voprosy Pitaniya. Problems of Nutrition. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11- 1952- Volume(issue)/page/year: 38(4),63,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5642 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 157 (estimated) No. of Female Employees: 72 (estimated)

 Safety Information

Symbol GHS02 GHS07 GHS08
GHS02, GHS07, GHS08
Signal Word Danger
Hazard Statements H225-H315-H360FD
Supplemental HS May form explosive peroxides.
Precautionary Statements P201-P210-P280-P308 + P313-P370 + P378-P403 + P235
Hazard Codes F,T
Risk Phrases 60-61-11-19-38
Safety Phrases 53-45
RIDADR 3249
WGK Germany 3
RTECS BV8000000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2942000000

 Customs

HS Code 2942000000

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 Synonyms

1-Dehydro-17a-methyltestosterone
Androsta-1,4-dien-3-one, 17β-hydroxy-17α-methyl-
Androsta-1,4-dien-3-one, 17β-hydroxy-17-methyl-
1-Dehydro-17α-methyltestosterone
Androsta-1,4-dien-3-one, 17-hydroxy-17-methyl-, (17β)-
EINECS 200-787-2
(17β)-17-Hydroxy-17-methylandrosta-1,4-dien-3-one
17a-Methyl-17b-hydroxyandrosta-1,4-dien-3-one
17-β-hydroxy-17-methyl-androsta-1,4-dien-3-one (9CI)
Metandienone
(17b)-17-Hydroxy-17-methylandrosta-1,4-dien-3-one
Nabolin
17-β-hydroxy-17-methyl-androsta-1,4-dien-3-one
Methandienone
Methandrostenolone
MFCD00003650
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Related Compounds: More...
Metandienone-d3
869287-60-5
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