Mastoparan X

Modify Date: 2026-07-04 08:58:41

Mastoparan X Structure
Mastoparan X structure
Common Name Mastoparan X
CAS Number 72093-22-2 Molecular Weight 1555.97000
Density 1.207 g/cm3 Boiling Point 1797.4ºC at 760 mmHg
Molecular Formula C73H126N20O15S Melting Point N/A
MSDS N/A Flash Point 1040.8ºC

 Use of Mastoparan X


Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells[1].

 Names

Name Mastoparan X
Synonym More Synonyms

 Mastoparan X Biological Activity

Description Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells[1].
Related Catalog
Target

GTP-binding regulatory protein (G protein)[1]

In Vitro Mastoparan X (1.5 mM) interacts with phospholipid bicelles, and results the line broadening[2]. Mastoparan X binds to the membrane, and increases the cell’s permeability to cations leading to a disruption in the electrolyte balance and cell lysis[2].
References

[1]. Wakamatsu K, et al. Membrane-bound conformation of mastoparan-X, a G-protein-activating peptide. Biochemistry. 1992 Jun 23;31(24):5654-60.  

[2]. Whiles JA, et al. Orientation and effects of mastoparan X on phospholipid bicelles. Biophys J. 2001 Jan;80(1):280-93.  

 Chemical & Physical Properties

Density 1.207 g/cm3
Boiling Point 1797.4ºC at 760 mmHg
Molecular Formula C73H126N20O15S
Molecular Weight 1555.97000
Flash Point 1040.8ºC
Exact Mass 1554.94000
PSA 609.65000
LogP 6.99990
Index of Refraction 1.558
InChIKey FYJKBFOGJAVCAL-UHFFFAOYSA-N
SMILES CCC(C)C(N)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCSC)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(N)=O)C(C)CC

 Safety Information

Safety Phrases 22-24/25

 Synthetic Route

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Mastoparan X Structure

Mastoparan X

CAS#:72093-22-2

Learn More
Literature: Yajima; Kanaki; Funakoshi; et al. Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 3 p. 882 - 886

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

DL-AP5 Sodium salt
H-ILE-ASN-TRP-LYS-GLY-ILE-ALA-ALA-MET-ALA-LYS-LYS-LEU-LEU-NH2
INWKGIAAMAKKLL-NH2
Ile-Asn-Trp-Lys-Gly-Ile-Ala-Ala-Met-Ala-Lys-Lys-Leu-Leu-NH2
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