9-Anthracenecarboxylic acid

Modify Date: 2024-01-02 12:41:59

9-Anthracenecarboxylic acid Structure
9-Anthracenecarboxylic acid structure
Common Name 9-Anthracenecarboxylic acid
CAS Number 723-62-6 Molecular Weight 222.239
Density 1.3±0.1 g/cm3 Boiling Point 467.5±14.0 °C at 760 mmHg
Molecular Formula C15H10O2 Melting Point 213-217 °C(lit.)
MSDS Chinese USA Flash Point 206.1±14.8 °C

 Use of 9-Anthracenecarboxylic acid


Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells[1].

 Names

Name 9-anthroic acid
Synonym More Synonyms

 9-Anthracenecarboxylic acid Biological Activity

Description Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells[1].
Related Catalog
Target

Ca2+-activated Cl- currents[1]

In Vitro Anthracene-9-carboxylic acid causes a voltage-dependent block of outward currents in HEK 293T cells and inhibits a larger fraction of the current as depolarization increased[1]. Anthracene-9-carboxylic acid induces a strong potentiation of tail currents measured at -100 mV after depolarizing voltages, as well as a prolongation of the deactivation kinetics in HEK 293T[1]. Anthracene-9-carboxylic acid (500 μM, rabbit pulmonary artery smooth muscle cells) produces a small inhibition of the maximum outward Cl- current at +70 mV (21±10%) but augmented the amplitude of the instantaneous inward relaxation at -80 mV by 321±34%[2].

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 467.5±14.0 °C at 760 mmHg
Melting Point 213-217 °C(lit.)
Molecular Formula C15H10O2
Molecular Weight 222.239
Flash Point 206.1±14.8 °C
Exact Mass 222.068085
PSA 37.30000
LogP 4.36
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.743
Water Solubility insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CB8764000
CHEMICAL NAME :
9-Anthroic acid
CAS REGISTRY NUMBER :
723-62-6
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C15-H10-O2
MOLECULAR WEIGHT :
222.25
WISWESSER LINE NOTATION :
L C666J BVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Behavioral - rigidity (including catalepsy) Behavioral - muscle contraction or spasticity

MUTATION DATA

TYPE OF TEST :
Phage inhibition capacity
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
127 ug/well
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 260,349,1991

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS CB8764000
HS Code 2916399090

 Synthetic Route

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles30

More Articles
Role of anoctamin-1 and bestrophin-1 in spinal nerve ligation-induced neuropathic pain in rats.

Mol. Pain 11 , 41, (2015)

Calcium-activated chloride channels (CaCCs) activation induces membrane depolarization by increasing chloride efflux in primary sensory neurons that can facilitate action potential generation. Previou...

Integrated microfluidic chip and online SCX separation allows untargeted nanoscale metabolomic and peptidomic profiling.

J. Proteome Res. 14(3) , 1621-6, (2015)

Metabolomics and peptidomics are systems biology approaches in which broad populations of molecular species produced in a cell or tissue sample are identified and quantified. These two molecular popul...

Extracellular magnesium and calcium reduce myotonia in isolated ClC-1 chloride channel-inhibited human muscle.

Muscle Nerve 51(1) , 65-71, (2015)

Experimental myotonia induced in rat muscle by ClC-1 chloride channel-inhibited has been shown to be related inversely to extracellular concentrations of Mg(2+) and Ca(2+) ([Mg(2+) ]o and [Ca(2+) ]o) ...

 Synonyms

9-Anthroic acid
EINECS 211-964-9
9-Carboxyanthracene
ANCA
anthracene-9-carboxylic acid
MFCD00001257
9-Anthracene carboxylic acid
anthracenecarboxylic acid
9-Anthracenecarboxylic acid
Polyoxyethylenesorbitan monolaurate
Top Suppliers:I want be here




Get all suppliers and price by the below link:

9-Anthracenecarboxylic acid suppliers


Price: ¥97/5g

Reference only. check more 9-Anthracenecarboxylic acid price