1,4-bis(benzenesulfonyl)piperazine

Modify Date: 2026-07-16 00:00:36

1,4-bis(benzenesulfonyl)piperazine Structure
1,4-bis(benzenesulfonyl)piperazine structure
Common Name 1,4-bis(benzenesulfonyl)piperazine
CAS Number 7250-99-9 Molecular Weight 366.45500
Density 1.392g/cm3 Boiling Point 552.6ºC at 760mmHg
Molecular Formula C16H18N2O4S2 Melting Point N/A
MSDS N/A Flash Point 288ºC

 Names

Name 1,4-bis(benzenesulfonyl)piperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.392g/cm3
Boiling Point 552.6ºC at 760mmHg
Molecular Formula C16H18N2O4S2
Molecular Weight 366.45500
Flash Point 288ºC
Exact Mass 366.07100
PSA 91.52000
LogP 3.41920
InChIKey JUQZKAOPUODWFG-UHFFFAOYSA-N
SMILES O=S(=O)(c1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1

 Synthetic Route

~39%

1,4-bis(benzenesulfonyl)piperazine Structure

1,4-bis(benzene...

CAS#:7250-99-9

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Literature: Singh, Paramjit; Jain, Anupa Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 790 - 792

~%

1,4-bis(benzenesulfonyl)piperazine Structure

1,4-bis(benzene...

CAS#:7250-99-9

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Literature: Chem. Fabr. Schering Patent: DE70055 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 952 Full Text Show Details Marckwald; v.Droste-Huelshoff Chemische Berichte, 1898 , vol. 31, p. 3262 Chem. Zentralbl., 1900 , vol. 71, # I p. 524

~%

1,4-bis(benzenesulfonyl)piperazine Structure

1,4-bis(benzene...

CAS#:7250-99-9

Learn More
Literature: Chem. Fabr. Schering Patent: DE70055 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 952 Full Text Show Details Marckwald; v.Droste-Huelshoff Chemische Berichte, 1898 , vol. 31, p. 3262 Chem. Zentralbl., 1900 , vol. 71, # I p. 524

~%

1,4-bis(benzenesulfonyl)piperazine Structure

1,4-bis(benzene...

CAS#:7250-99-9

Learn More
Literature: Chem. Fabr. Schering Patent: DE70055 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 952

~%

1,4-bis(benzenesulfonyl)piperazine Structure

1,4-bis(benzene...

CAS#:7250-99-9

Learn More
Literature: Chem. Fabr. Schering Patent: DE70055 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 952

 1,4-bis(benzenesulfonyl)piperazineBioassay

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Name: qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1):...
Source: NCGC
Target: thioredoxin reductase [Rattus norvegicus]
External Id: TRXR101
Name: qHTS screening for TAG (triacylglycerol) accumulators in algae
Source: 11812
Target: N/A
External Id: FATTTLab-Algae-Lipid
Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
Name: qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation.
Source: NCGC
Target: N/A
External Id: GIAR101
Name: qHTS for Inhibitors of Polymerase Iota
Source: NCGC
Target: DNA polymerase iota [Homo sapiens]
External Id: PolI100
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primar...
Source: NCGC
Target: 67.9K protein [Vaccinia virus]
External Id: Vaccinia-p2mCherry
Name: Small-molecule inhibitors of ST2 (IL1RL1)
Source: 20881
Target: interleukin-1 receptor-like 1 isoform [homo sapiens]
External Id: ST2_IL33_Inhibitors_Primary_Screening_77700
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100
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 Synonyms

1,4-bis-benzenesulfonyl-piperazine
N.N'-Dibenzolsulfonyl-piperazin
1,4-Bis-benzolsulfonyl-piperazin
F0046-0029
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