GADOTERIC ACID

Modify Date: 2024-01-05 14:18:57

GADOTERIC ACID Structure
GADOTERIC ACID structure
Common Name GADOTERIC ACID
CAS Number 72573-82-1 Molecular Weight 558.64200
Density N/A Boiling Point 701.6ºC at 760 mmHg
Molecular Formula C16H25GdN4O8 Melting Point N/A
MSDS N/A Flash Point 378.1ºC

 Use of GADOTERIC ACID


Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. In particular, Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution[1][2].

 Names

Name Gadoteric acid
Synonym More Synonyms

 GADOTERIC ACID Biological Activity

Description Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. In particular, Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution[1][2].
Related Catalog
In Vitro 在肝细胞癌(尤其是高血管病变)的 DCE-MRI 中,Gadoteric acid 提供了更好的,更明显的对比度,以及早期增强的可感知性和更强的冲洗性[1]。
References

[1]. Federico Collettini, et al. MR imaging of hepatocellular carcinoma: prospective intraindividual head-to-head comparison of the contrast agents gadoxetic acid and gadoteric acid. Sci Rep. 2022 Nov 3;12(1):18583.  

[2]. Martin Maurer, et al. Tolerability and diagnostic value of gadoteric acid in the general population and in patients with risk factors: results in more than 84,000 patients. Eur J Radiol. 2012 May;81(5):885-90.  

 Chemical & Physical Properties

Boiling Point 701.6ºC at 760 mmHg
Molecular Formula C16H25GdN4O8
Molecular Weight 558.64200
Flash Point 378.1ºC
Exact Mass 559.09100
PSA 160.93000
Storage condition 2-8°C

 Synonyms

Gadolinium 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetic acid
Gadoteric
gadolinium(III) 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid