Effusol

Modify Date: 2024-01-02 11:48:13

Effusol structure	Common Name	Effusol
	CAS Number	73166-28-6	Molecular Weight	252.30800
	Density	1.229g/cm3	Boiling Point	508.9ºC at 760 mmHg
	Molecular Formula	C₁₇H₁₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	248.4ºC

Use of Effusol

Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline[1].

Name	5-ethenyl-1-methyl-9,10-dihydrophenanthrene-2,7-diol
Synonym	More Synonyms

Description	Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Kim, Ye Jin, et al. Antioxidant and Cytotoxic Activity of Compounds from the Stem of Juncus effuses. Journal of Applied Biological Chemistry. Volume 57 Issue 1 / Pages.47-51 / 2014 / 1976-0442(pISSN). [2]. Haruna Tamano, et al. CA1 LTP Attenuated by Corticosterone Is Canceled by Effusol via Rescuing Intracellular Zn 2+ Dysregulation. Cell Mol Neurobiol. 2019 Oct;39(7):975-983.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

References

[1]. Kim, Ye Jin, et al. Antioxidant and Cytotoxic Activity of Compounds from the Stem of Juncus effuses. Journal of Applied Biological Chemistry. Volume 57 Issue 1 / Pages.47-51 / 2014 / 1976-0442(pISSN).

[2]. Haruna Tamano, et al. CA1 LTP Attenuated by Corticosterone Is Canceled by Effusol via Rescuing Intracellular Zn 2+ Dysregulation. Cell Mol Neurobiol. 2019 Oct;39(7):975-983.

Density	1.229g/cm3
Boiling Point	508.9ºC at 760 mmHg
Molecular Formula	C₁₇H₁₆O₂
Molecular Weight	252.30800
Flash Point	248.4ºC
Exact Mass	252.11500
PSA	40.46000
LogP	3.81480
Index of Refraction	1.684